Cargando…

Downregulation of miR-654-3p in Colorectal Cancer Indicates Poor Prognosis and Promotes Cell Proliferation and Invasion by Targeting SRC

BACKGROUND: MicroRNAs (miRNAs), such as miR-654-3p, regulate gene expression at the post-transcriptional level affecting malignant tumor behavior. However, the expression levels, function, and mechanism of miR-654-3p in colorectal cancer (CRC) are unknown. METHODS: The expression levels of miR-654-3...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Haoran, Shen, Zhanlong, Zhou, Yushi, Zhang, Zhen, Wang, Quan, Zhang, Mengmeng, Jiang, Kewei, Wang, Shan, Ye, Yingjiang, Wang, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554538/ https://www.ncbi.nlm.nih.gov/pubmed/33193697 http://dx.doi.org/10.3389/fgene.2020.577948

Ejemplares similares

Molecular Characterization and Clinical Relevance of RNA Binding Proteins in Colorectal Cancer
por: Zhang, Zhen, et al.
Publicado: (2020)

Lnc-HSD17B11-1:1 Functions as a Competing Endogenous RNA to Promote Colorectal Cancer Progression by Sponging miR-338-3p to Upregulate MACC1
por: Zhang, Wei, et al.
Publicado: (2020)

Landscape of cell heterogeneity and evolutionary trajectory in ulcerative colitis-associated colon cancer revealed by single-cell RNA sequencing
por: Wang, Quan, et al.
Publicado: (2021)

hsa_circ_0000231 Promotes colorectal cancer cell growth through upregulation of CCND2 by IGF2BP3/miR-375 dual pathway
por: Zhang, Wei, et al.
Publicado: (2022)

MiR-654-3p Constrains Proliferation, Invasion, and Migration of Sinonasal Squamous Cell Carcinoma via CREB1/PSEN1 Regulatory Axis
por: Cui, Xiao, et al.
Publicado: (2022)

High Expression of TMEM33 Predicts Poor Prognosis and Promotes Cell Proliferation in Cervical Cancer
por: Chen, Hanxiang, et al.
Publicado: (2022)

Development and verification of a prognostic model for colon cancer on pyroptosis-related genes
por: Wu, Zizhen, et al.
Publicado: (2022)

N6‐methyladenosine demethylase ALKBH5 suppresses colorectal cancer progression potentially by decreasing PHF20 mRNA methylation
por: Zhang, Zhen, et al.
Publicado: (2022)

High GTSE1 expression promotes cell proliferation, metastasis and cisplatin resistance in ccRCC and is associated with immune infiltrates and poor prognosis
por: Lei, Pu, et al.
Publicado: (2023)

Poor prognosis, hypomethylation, and immune infiltrates are associated with downregulation of INMT in head and neck squamous cell carcinoma
por: Cui, Kun, et al.
Publicado: (2022)

Quantitative proteomic analysis of aberrant expressed lysine acetylation in gastrointestinal stromal tumors
por: Wang, Bo, et al.
Publicado: (2021)

TIMP1 Indicates Poor Prognosis of Renal Cell Carcinoma and Accelerates Tumorigenesis via EMT Signaling Pathway
por: Shou, Yi, et al.
Publicado: (2022)

NEAT1 Overexpression Indicates a Poor Prognosis and Induces Chemotherapy Resistance via the miR-491-5p/SOX3 Signaling Pathway in Ovarian Cancer
por: Jia, Xinzhuan, et al.
Publicado: (2021)

Cuproptosis patterns and tumor immune infiltration characterization in colorectal cancer
por: Du, Yan, et al.
Publicado: (2022)

Hypoxia-Induced miR-148a Downregulation Contributes to Poor Survival in Colorectal Cancer
por: Nersisyan, Stepan, et al.
Publicado: (2021)

miR-654-5p Contributes to the Activation and Proliferation of Hepatic Stellate Cells by Targeting RXRα
por: Ma, Heming, et al.
Publicado: (2022)

Increased ATP2A1 Predicts Poor Prognosis in Patients With Colorectal Carcinoma
por: Zhang, Guoshun, et al.
Publicado: (2022)

The overexpression of GPX8 is correlated with poor prognosis in GBM patients
por: Li, Sibo, et al.
Publicado: (2022)

Downregulation of miR-1826 Indicates a Poor Prognosis for Osteosarcoma Patients and Regulates Tumor Cell Proliferation, Migration, and Invasion
por: Li, Peng, et al.
Publicado: (2020)

miR-21-5p/PRKCE axis implicated in immune infiltration and poor prognosis of kidney renal clear cell carcinoma
por: Wang, Jinxiang, et al.
Publicado: (2022)

The clonal expression genes associated with poor prognosis of liver cancer
por: Zhang, Wanfeng, et al.
Publicado: (2022)

T cell proliferation-related genes: Predicting prognosis, identifying the cold and hot tumors, and guiding treatment in clear cell renal cell carcinoma
por: Huang, Haoran, et al.
Publicado: (2022)

Young adults with colon cancer: clinical features and surgical outcomes
por: Wang, Chao, et al.
Publicado: (2023)

High expression of KNL1 in prostate adenocarcinoma is associated with poor prognosis and immune infiltration
por: Zhang, Yetao, et al.
Publicado: (2023)

MiR-455-3p downregulation facilitates cell proliferation and invasion and predicts poor prognosis of osteosarcoma
por: Yi, Xijun, et al.
Publicado: (2020)

Non-coding ribonucleic acid-mediated CAMSAP1 upregulation leads to poor prognosis with suppressed immune infiltration in liver hepatocellular carcinoma
por: Wang, Wenwen, et al.
Publicado: (2022)

Upregulation of LIMK1 Is Correlated With Poor Prognosis and Immune Infiltrates in Lung Adenocarcinoma
por: Lu, Guojun, et al.
Publicado: (2021)

The cuproptosis-related signature predicts prognosis and indicates immune microenvironment in breast cancer
por: Li, Jia, et al.
Publicado: (2022)

High Expression of FCRLB Predicts Poor Prognosis in Patients With Colorectal Cancer
por: Wang, Xiaopeng, et al.
Publicado: (2022)

Amplification of the CD24 Gene Is an Independent Predictor for Poor Prognosis of Breast Cancer
por: Zhang, Peng, et al.
Publicado: (2019)

Integrative Clustering Reveals a Novel Subtype of Soft Tissue Sarcoma With Poor Prognosis
por: Zhu, Zhenhua, et al.
Publicado: (2020)

Downregulation of PSCA promotes gastric cancer proliferation and is related to poor prognosis
por: Xu, Li-pu, et al.
Publicado: (2020)

TMED2/9/10 Serve as Biomarkers for Poor Prognosis in Head and Neck Squamous Carcinoma
por: Gao, Wen, et al.
Publicado: (2022)

LCMT1 indicates poor prognosis and is essential for cell proliferation in hepatocellular carcinoma
por: Zhang, Ning, et al.
Publicado: (2022)

Investigating CENPW as a Novel Biomarker Correlated With the Development and Poor Prognosis of Breast Carcinoma
por: Wang, Luyang, et al.
Publicado: (2022)

Retraction: NEAT1 Overexpression Indicates a Poor Prognosis and Induces Chemotherapy Resistance via the miR-491-5p/SOX3 Signaling Pathway in Ovarian Cancer
por: Frontiers Editorial Office,
Publicado: (2022)

High Expression of PLAGL2 is Associated With Poor Prognosis in High-Grade Glioma
por: Wang, Gang, et al.
Publicado: (2022)

THBS2 is Closely Related to the Poor Prognosis and Immune Cell Infiltration of Gastric Cancer
por: Zhang, Shiyu, et al.
Publicado: (2022)

TP53 R273C Mutation Is Associated With Poor Prognosis in LGG Patients
por: Zhang, Jian, et al.
Publicado: (2022)

A Potential Indicator ARRDC2 Has Feasibility to Evaluate Prognosis and Immune Microenvironment in Ovarian Cancer
por: Zhang, Mengjun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7mriu4frqfslj0gabkgcgp4gln