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Airway Mucins Inhibit Oxidative and Non-Oxidative Bacterial Killing by Human Neutrophils

Neutrophil killing of bacteria is mediated by oxidative and non-oxidative mechanisms. Oxidants are generated through the NADPH oxidase complex, whereas antimicrobial proteins and peptides rank amongst non-oxidative host defenses. Mucus hypersecretion, deficient hydration and poor clearance from the...

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Detalles Bibliográficos
Autores principales:	Cantin, André M., Ouellet, Cristine, Cloutier, Alexandre, McDonald, Patrick P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554606/ https://www.ncbi.nlm.nih.gov/pubmed/33101020 http://dx.doi.org/10.3389/fphar.2020.554353

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