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An Increased Burden of Highly Active Retrotransposition Competent L1s Is Associated with Parkinson’s Disease Risk and Progression in the PPMI Cohort

Long interspersed element-1 (LINE-1/L1s) contributes 17% of the human genome with more than 1 million elements present; however, fewer than 100 of these have evidence for being retrotransposition competent (RC). In addition to those RC-L1s present in the reference genome, there are a small number of...

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Detalles Bibliográficos
Autores principales:	Pfaff, Abigail L., Bubb, Vivien J., Quinn, John P., Koks, Sulev
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554759/ https://www.ncbi.nlm.nih.gov/pubmed/32911699 http://dx.doi.org/10.3390/ijms21186562

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