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4-Hydroxynonenal Immunoreactivity Is Increased in the Frontal Cortex of 5XFAD Transgenic Mice

Oxidative stress was implicated in the functional impairment of the frontal cortex observed in early Alzheimer’s disease (AD). To elucidate this role in an animal AD model, we assessed cognitive function of 4-month-old five familial AD (5XFAD) transgenic (Tg) mice using a learning strategy-switching...

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Detalles Bibliográficos
Autores principales:	Shin, Sang-Wook, Kim, Dong-Hee, Jeon, Won Kyung, Han, Jung-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554765/ https://www.ncbi.nlm.nih.gov/pubmed/32899155 http://dx.doi.org/10.3390/biomedicines8090326

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