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Sulforaphane Inhibits MGO-AGE-Mediated Neuroinflammation by Suppressing NF-κB, MAPK, and AGE–RAGE Signaling Pathways in Microglial Cells
Advanced glycation end products (AGEs) are produced through the binding of glycated protein or lipid with sugar, and they are known to be involved in the pathogenesis of both age-dependent and independent neurological complications. Among dicarbonyl compounds, methylglyoxal (MGO), which is produced...
Autores principales: | Subedi, Lalita, Lee, Jae Hyuk, Gaire, Bhakta Prasad, Kim, Sun Yeou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554773/ https://www.ncbi.nlm.nih.gov/pubmed/32859007 http://dx.doi.org/10.3390/antiox9090792 |
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