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Anti-Inflammatory Activity of Kurarinone Involves Induction of HO-1 via the KEAP1/Nrf2 Pathway
Kurarinone, a flavonoid isolated from the roots of Sophora flavescens, was suggested to exert potent antioxidant and immunosuppressive effects. However, the underlying mechanisms remain unclear. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key transcription factor that regulates the antio...
Autores principales: | Nishikawa, Sakiko, Inoue, Yasumichi, Hori, Yuka, Miyajima, Chiharu, Morishita, Daisuke, Ohoka, Nobumichi, Hida, Shigeaki, Makino, Toshiaki, Hayashi, Hidetoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554885/ https://www.ncbi.nlm.nih.gov/pubmed/32916869 http://dx.doi.org/10.3390/antiox9090842 |
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