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Mitochondrial Transfer by Human Mesenchymal Stromal Cells Ameliorates Hepatocyte Lipid Load in a Mouse Model of NASH

Mesenchymal stromal cell (MSC) transplantation ameliorated hepatic lipid load; tissue inflammation; and fibrosis in rodent animal models of non-alcoholic steatohepatitis (NASH) by as yet largely unknown mechanism(s). In a mouse model of NASH; we transplanted bone marrow-derived MSCs into the livers;...

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Detalles Bibliográficos
Autores principales:	Hsu, Mei-Ju, Karkossa, Isabel, Schäfer, Ingo, Christ, Madlen, Kühne, Hagen, Schubert, Kristin, Rolle-Kampczyk, Ulrike E., Kalkhof, Stefan, Nickel, Sandra, Seibel, Peter, von Bergen, Martin, Christ, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554948/ https://www.ncbi.nlm.nih.gov/pubmed/32937969 http://dx.doi.org/10.3390/biomedicines8090350

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