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DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes
This study aimed to establish the Dual-Energy X-ray Absorptiometry (DXA)-derived Visceral adipose tissue (VAT) reference values for gender and assess the metabolic outcomes associated to the VAT in a cohort of elderly patients. The sample included 795 elderly patients (226/569: men/women) aged 65–10...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554982/ https://www.ncbi.nlm.nih.gov/pubmed/32846931 http://dx.doi.org/10.3390/life10090163 |
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author | Spadaccini, Daniele Perna, Simone Peroni, Gabriella D’Antona, Giuseppe Iannello, Giancarlo Faragli, Alessandro Infantino, Vittoria Riva, Antonella Petrangolini, Giovanna Negro, Massimo Gasparri, Clara Rondanelli, Mariangela |
author_facet | Spadaccini, Daniele Perna, Simone Peroni, Gabriella D’Antona, Giuseppe Iannello, Giancarlo Faragli, Alessandro Infantino, Vittoria Riva, Antonella Petrangolini, Giovanna Negro, Massimo Gasparri, Clara Rondanelli, Mariangela |
author_sort | Spadaccini, Daniele |
collection | PubMed |
description | This study aimed to establish the Dual-Energy X-ray Absorptiometry (DXA)-derived Visceral adipose tissue (VAT) reference values for gender and assess the metabolic outcomes associated to the VAT in a cohort of elderly patients. The sample included 795 elderly patients (226/569: men/women) aged 65–100 years (mean age 80.9 ± 7.5ys). Body composition measures and VAT were assessed by DXA and Core-Scan software. Biochemical analysis and a multidimensional comprehensive geriatric assessment were performed. VAT percentiles at the level of 5, 25, 50, 75, 95 were found in males at the following levels: 246, 832, 1251, 1769, 3048 cm(3) and for females at 99, 476, 775, 1178, 2277 cm(3). Moreover, this study showed that DXA-VAT was associated to a worsening of lipid, glycemic, hematocrit and kidney profile. Further studies will be needed in order to implement these findings in order to define the (DXA)-derived VAT levels associated to the frailty related risk factors in elderly. |
format | Online Article Text |
id | pubmed-7554982 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-75549822020-10-14 DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes Spadaccini, Daniele Perna, Simone Peroni, Gabriella D’Antona, Giuseppe Iannello, Giancarlo Faragli, Alessandro Infantino, Vittoria Riva, Antonella Petrangolini, Giovanna Negro, Massimo Gasparri, Clara Rondanelli, Mariangela Life (Basel) Article This study aimed to establish the Dual-Energy X-ray Absorptiometry (DXA)-derived Visceral adipose tissue (VAT) reference values for gender and assess the metabolic outcomes associated to the VAT in a cohort of elderly patients. The sample included 795 elderly patients (226/569: men/women) aged 65–100 years (mean age 80.9 ± 7.5ys). Body composition measures and VAT were assessed by DXA and Core-Scan software. Biochemical analysis and a multidimensional comprehensive geriatric assessment were performed. VAT percentiles at the level of 5, 25, 50, 75, 95 were found in males at the following levels: 246, 832, 1251, 1769, 3048 cm(3) and for females at 99, 476, 775, 1178, 2277 cm(3). Moreover, this study showed that DXA-VAT was associated to a worsening of lipid, glycemic, hematocrit and kidney profile. Further studies will be needed in order to implement these findings in order to define the (DXA)-derived VAT levels associated to the frailty related risk factors in elderly. MDPI 2020-08-24 /pmc/articles/PMC7554982/ /pubmed/32846931 http://dx.doi.org/10.3390/life10090163 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Spadaccini, Daniele Perna, Simone Peroni, Gabriella D’Antona, Giuseppe Iannello, Giancarlo Faragli, Alessandro Infantino, Vittoria Riva, Antonella Petrangolini, Giovanna Negro, Massimo Gasparri, Clara Rondanelli, Mariangela DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes |
title | DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes |
title_full | DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes |
title_fullStr | DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes |
title_full_unstemmed | DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes |
title_short | DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes |
title_sort | dxa-derived visceral adipose tissue (vat) in elderly: percentiles of reference for gender and association with metabolic outcomes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554982/ https://www.ncbi.nlm.nih.gov/pubmed/32846931 http://dx.doi.org/10.3390/life10090163 |
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