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DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes

This study aimed to establish the Dual-Energy X-ray Absorptiometry (DXA)-derived Visceral adipose tissue (VAT) reference values for gender and assess the metabolic outcomes associated to the VAT in a cohort of elderly patients. The sample included 795 elderly patients (226/569: men/women) aged 65–10...

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Autores principales: Spadaccini, Daniele, Perna, Simone, Peroni, Gabriella, D’Antona, Giuseppe, Iannello, Giancarlo, Faragli, Alessandro, Infantino, Vittoria, Riva, Antonella, Petrangolini, Giovanna, Negro, Massimo, Gasparri, Clara, Rondanelli, Mariangela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554982/
https://www.ncbi.nlm.nih.gov/pubmed/32846931
http://dx.doi.org/10.3390/life10090163
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author Spadaccini, Daniele
Perna, Simone
Peroni, Gabriella
D’Antona, Giuseppe
Iannello, Giancarlo
Faragli, Alessandro
Infantino, Vittoria
Riva, Antonella
Petrangolini, Giovanna
Negro, Massimo
Gasparri, Clara
Rondanelli, Mariangela
author_facet Spadaccini, Daniele
Perna, Simone
Peroni, Gabriella
D’Antona, Giuseppe
Iannello, Giancarlo
Faragli, Alessandro
Infantino, Vittoria
Riva, Antonella
Petrangolini, Giovanna
Negro, Massimo
Gasparri, Clara
Rondanelli, Mariangela
author_sort Spadaccini, Daniele
collection PubMed
description This study aimed to establish the Dual-Energy X-ray Absorptiometry (DXA)-derived Visceral adipose tissue (VAT) reference values for gender and assess the metabolic outcomes associated to the VAT in a cohort of elderly patients. The sample included 795 elderly patients (226/569: men/women) aged 65–100 years (mean age 80.9 ± 7.5ys). Body composition measures and VAT were assessed by DXA and Core-Scan software. Biochemical analysis and a multidimensional comprehensive geriatric assessment were performed. VAT percentiles at the level of 5, 25, 50, 75, 95 were found in males at the following levels: 246, 832, 1251, 1769, 3048 cm(3) and for females at 99, 476, 775, 1178, 2277 cm(3). Moreover, this study showed that DXA-VAT was associated to a worsening of lipid, glycemic, hematocrit and kidney profile. Further studies will be needed in order to implement these findings in order to define the (DXA)-derived VAT levels associated to the frailty related risk factors in elderly.
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spelling pubmed-75549822020-10-14 DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes Spadaccini, Daniele Perna, Simone Peroni, Gabriella D’Antona, Giuseppe Iannello, Giancarlo Faragli, Alessandro Infantino, Vittoria Riva, Antonella Petrangolini, Giovanna Negro, Massimo Gasparri, Clara Rondanelli, Mariangela Life (Basel) Article This study aimed to establish the Dual-Energy X-ray Absorptiometry (DXA)-derived Visceral adipose tissue (VAT) reference values for gender and assess the metabolic outcomes associated to the VAT in a cohort of elderly patients. The sample included 795 elderly patients (226/569: men/women) aged 65–100 years (mean age 80.9 ± 7.5ys). Body composition measures and VAT were assessed by DXA and Core-Scan software. Biochemical analysis and a multidimensional comprehensive geriatric assessment were performed. VAT percentiles at the level of 5, 25, 50, 75, 95 were found in males at the following levels: 246, 832, 1251, 1769, 3048 cm(3) and for females at 99, 476, 775, 1178, 2277 cm(3). Moreover, this study showed that DXA-VAT was associated to a worsening of lipid, glycemic, hematocrit and kidney profile. Further studies will be needed in order to implement these findings in order to define the (DXA)-derived VAT levels associated to the frailty related risk factors in elderly. MDPI 2020-08-24 /pmc/articles/PMC7554982/ /pubmed/32846931 http://dx.doi.org/10.3390/life10090163 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Spadaccini, Daniele
Perna, Simone
Peroni, Gabriella
D’Antona, Giuseppe
Iannello, Giancarlo
Faragli, Alessandro
Infantino, Vittoria
Riva, Antonella
Petrangolini, Giovanna
Negro, Massimo
Gasparri, Clara
Rondanelli, Mariangela
DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes
title DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes
title_full DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes
title_fullStr DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes
title_full_unstemmed DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes
title_short DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes
title_sort dxa-derived visceral adipose tissue (vat) in elderly: percentiles of reference for gender and association with metabolic outcomes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554982/
https://www.ncbi.nlm.nih.gov/pubmed/32846931
http://dx.doi.org/10.3390/life10090163
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