Cargando…

Activate or Inhibit? Implications of Autophagy Modulation as a Therapeutic Strategy for Alzheimer’s Disease

Neurodegenerative diseases result in a range of conditions depending on the type of proteinopathy, genes affected or the location of the degeneration in the brain. Proteinopathies such as senile plaques and neurofibrillary tangles in the brain are prominent features of Alzheimer’s disease (AD). Auto...

Descripción completa

Detalles Bibliográficos
Autores principales:	Krishnan, Sharmeelavathi, Shrestha, Yasaswi, Jayatunga, Dona P. W., Rea, Sarah, Martins, Ralph, Bharadwaj, Prashant
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554997/ https://www.ncbi.nlm.nih.gov/pubmed/32937909 http://dx.doi.org/10.3390/ijms21186739

Ejemplares similares

Mitoprotective Effects of a Synergistic Nutraceutical Combination: Basis for a Prevention Strategy Against Alzheimer’s Disease
por: Jayatunga, Dona P. W., et al.
Publicado: (2022)

Autophagy Modulation as a Treatment of Amyloid Diseases
por: Mputhia, Zoe, et al.
Publicado: (2019)

Therapeutic Potential of Mitophagy-Inducing Microflora Metabolite, Urolithin A for Alzheimer’s Disease
por: Jayatunga, Dona Pamoda W., et al.
Publicado: (2021)

Aβ aggregation and possible implications in Alzheimer's disease pathogenesis
por: Bharadwaj, Prashant R, et al.
Publicado: (2009)

A Synergistic Combination of DHA, Luteolin, and Urolithin A Against Alzheimer’s Disease
por: Jayatunga, Dona P. W., et al.
Publicado: (2022)

PRKAG2 Gene Expression Is Elevated and its Protein Levels Are Associated with Increased Amyloid-β Accumulation in the Alzheimer’s Disease Brain
por: Bharadwaj, Prashant, et al.
Publicado: (2020)

The Switch between Protective and Nonprotective Autophagy; Implications for Autophagy Inhibition as a Therapeutic Strategy in Cancer
por: Gewirtz, David A.
Publicado: (2020)

Autophagy and Alzheimer’s Disease: From Molecular Mechanisms to Therapeutic Implications
por: Uddin, Md. Sahab, et al.
Publicado: (2018)

Implications on the Therapeutic Potential of Statins via Modulation of Autophagy
por: Gorabi, Armita Mahdavi, et al.
Publicado: (2021)

Autophagy in dry eye disease: Therapeutic implications of autophagy modulators on the ocular surface
por: Jeyabalan, Nallathambi, et al.
Publicado: (2023)

Autophagy Modulation in Aggresome Formation: Emerging Implications and Treatments of Alzheimer’s Disease
por: Rahman, Md. Ataur, et al.
Publicado: (2022)

Inhibition of Bruton’s Tyrosine Kinase Modulates Microglial Phagocytosis: Therapeutic Implications for Alzheimer’s Disease
por: Keaney, James, et al.
Publicado: (2019)

The Cytoprotective, Cytotoxic and Nonprotective Functional Forms of Autophagy Induced by Microtubule Poisons in Tumor Cells—Implications for Autophagy Modulation as a Therapeutic Strategy
por: Xu, Jingwen, et al.
Publicado: (2022)

Modulation of autophagy as a therapeutic strategy for Toxoplasma gondii infection
por: Cheng, Ao, et al.
Publicado: (2022)

A rapid absorbance-based growth assay to screen the toxicity of oligomer Aβ(42) and protect against cell death in yeast
por: Bharadwaj, Prashant, et al.
Publicado: (2020)

Is Autophagy Inhibition in Combination with Temozolomide a Therapeutically Viable Strategy?
por: Elshazly, Ahmed M., et al.
Publicado: (2023)

Therapeutic Implications of Renin–Angiotensin System Modulators in Alzheimer’s Dementia
por: Ababei, Daniela-Carmen, et al.
Publicado: (2023)

Modulation of mitochondrial bioenergetics as a therapeutic strategy in Alzheimer's disease
por: Onyango, Isaac G.
Publicado: (2018)

Targeting autophagy: a novel anticancer strategy with therapeutic implications for imatinib resistance
por: Carew, Jennifer S, et al.
Publicado: (2008)

BACE1 inhibition as a therapeutic strategy for Alzheimer's disease
por: Vassar, Robert
Publicado: (2016)

Influence of Vertebrate Excreta on Attraction, Oviposition and Development of the Asian Tiger Mosquito, Aedes albopictus (Diptera: Culicidae)
por: Rajapaksha, R. Dulka T., et al.
Publicado: (2021)

A Therapeutic Strategy for Alzheimer's Disease Focused on Immune-inflammatory Modulation
por: Kim, Seung Hyun, et al.
Publicado: (2019)

Therapeutic implication of autophagy in neurodegenerative diseases
por: Rahman, Md. Ataur, et al.
Publicado: (2017)

Neuroprotective Herbs for the Management of Alzheimer’s Disease
por: Gregory, Julie, et al.
Publicado: (2021)

Therapeutic Implications of Probiotics in the Gut Microbe-Modulated Neuroinflammation and Progression of Alzheimer’s Disease
por: Murai, Toshiyuki, et al.
Publicado: (2023)

Pim1 inhibition as a novel therapeutic strategy for Alzheimer’s disease
por: Velazquez, Ramon, et al.
Publicado: (2016)

Autophagy Modulation as a Potential Therapeutic Strategy in Osteosarcoma: Current Insights and Future Perspectives
por: Almansa-Gómez, Sergio, et al.
Publicado: (2023)

Therapeutic Modulation of Autophagy in Leukaemia and Lymphoma
por: Djavaheri-Mergny, Mojgan, et al.
Publicado: (2019)

Therapeutic Potential of Autophagy Modulation in Cholangiocarcinoma
por: Perez-Montoyo, Hector
Publicado: (2020)

Autophagy and ALS: mechanistic insights and therapeutic implications
por: Chua, Jason P., et al.
Publicado: (2021)

Autophagy Modulation and Its Implications on Glioblastoma Treatment
por: Chen, Johnny, et al.
Publicado: (2023)

Skeletal Muscle Homeostasis in Duchenne Muscular Dystrophy: Modulating Autophagy as a Promising Therapeutic Strategy
por: De Palma, Clara, et al.
Publicado: (2014)

Alterations and Interchange of Morphometric Characters in Different Life Cycle Stages with Reference to Genomic Variations of Anopheles subpictus (Diptera; Culicidae) Sibling Species Complex in Sri Lanka
por: Jayatunga, Dona P. W., et al.
Publicado: (2018)

Multitarget therapeutic strategies for Alzheimer’s disease
por: Ibrahim, Mostafa M., et al.
Publicado: (2019)

Allosteric Modulation of Neurotransmitter Transporters as a Therapeutic Strategy
por: Niello, Marco, et al.
Publicado: (2020)

Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles
por: Deng, Zhiqiang, et al.
Publicado: (2022)

Modulating autophagy: a strategy for cancer therapy
por: Li, Jun-Lin, et al.
Publicado: (2011)

Levofolene modulates apoptosis induced by 5-fluorouracil through autophagy inhibition: Clinical and occupational implications
por: LAMBERTI, MONICA, et al.
Publicado: (2015)

Insight Into the Role of Autophagy in Osteosarcoma and Its Therapeutic Implication
por: Niu, Jianfang, et al.
Publicado: (2019)

Autophagy in Heart Failure: Insights into Mechanisms and Therapeutic Implications
por: Bielawska, Magdalena, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0ifgq6namjfrfu1l9ou3andffd