Nephroprotective Effect of Cilastatin against Gentamicin-Induced Renal Injury In Vitro and In Vivo without Altering Its Bactericidal Efficiency

Gentamicin is a used antibiotic that causes nephrotoxicity in 10–20% of treatment periods, which limits its use considerably. Our results have shown that cilastatin may be a promising therapeutic alternative in toxin-induced acute kidney injury (AKI). Here, we investigated its potential use as a nep...

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Detalles Bibliográficos
Autores principales: Jado, Juan Carlos, Humanes, Blanca, González-Nicolás, María Ángeles, Camaño, Sonia, Lara, José Manuel, López, Beatriz, Cercenado, Emilia, García-Bordas, Julio, Tejedor, Alberto, Lázaro, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555100/
https://www.ncbi.nlm.nih.gov/pubmed/32899204
http://dx.doi.org/10.3390/antiox9090821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555100/
https://www.ncbi.nlm.nih.gov/pubmed/32899204
http://dx.doi.org/10.3390/antiox9090821

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