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p50 suppresses cytotoxic T lymphocyte effector function to regulate tumor immune escape and response to immunotherapy
BACKGROUND: NF-κB is a key link between inflammation and cancer. Previous studies of NF-κB have largely focused on tumor cells, and the intrinsic function of NF-κB in T cells in tumor development and response to immunotherapy is largely unknown. We aimed at testing the hypothesis that NF-κB1 (p50) a...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BMJ Publishing Group
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555101/ https://www.ncbi.nlm.nih.gov/pubmed/33051343 http://dx.doi.org/10.1136/jitc-2020-001365 |