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Mitochondrial Surveillance by Cdc48/p97: MAD vs. Membrane Fusion
Cdc48/p97 is a ring-shaped, ATP-driven hexameric motor, essential for cellular viability. It specifically unfolds and extracts ubiquitylated proteins from membranes or protein complexes, mostly targeting them for proteolytic degradation by the proteasome. Cdc48/p97 is involved in a multitude of cell...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555132/ https://www.ncbi.nlm.nih.gov/pubmed/32961852 http://dx.doi.org/10.3390/ijms21186841 |