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Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio

In current clinical practice, orthopedic surgeons often delay the surgery intervention on geriatric hip fracture patients to optimize the international normalized ratio (INR), in order to decrease the risk of postoperative hematological complications. However, some evidence suggests that full revers...

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Autores principales: Kain, Michael S., Saper, David, Lybrand, Kyle, Bramlett, Kasey-Jean, Tornetta III, Paul, Althausen, Peter, Garfi, John S., Willier III, Donald P., Niu, Ruijia, Marcantonio, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555195/
https://www.ncbi.nlm.nih.gov/pubmed/32679667
http://dx.doi.org/10.3390/geriatrics5030043
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author Kain, Michael S.
Saper, David
Lybrand, Kyle
Bramlett, Kasey-Jean
Tornetta III, Paul
Althausen, Peter
Garfi, John S.
Willier III, Donald P.
Niu, Ruijia
Marcantonio, Andrew J.
author_facet Kain, Michael S.
Saper, David
Lybrand, Kyle
Bramlett, Kasey-Jean
Tornetta III, Paul
Althausen, Peter
Garfi, John S.
Willier III, Donald P.
Niu, Ruijia
Marcantonio, Andrew J.
author_sort Kain, Michael S.
collection PubMed
description In current clinical practice, orthopedic surgeons often delay the surgery intervention on geriatric hip fracture patients to optimize the international normalized ratio (INR), in order to decrease the risk of postoperative hematological complications. However, some evidence suggests that full reversal protocols may not be necessary, especially for patients with prior thromboembolic history. Our study aims to compare the surgical outcomes of patients with normal versus elevated INR values. We conducted a retrospective chart review on 217 patients who underwent surgeries on hip fractures at two academic trauma centers. We found that in our group (n = 124) of patients with an INR value of 1.5–3.0, there was only one reoperation for a hematoma, but there was a trend for more blood transfusions. There was no statistically significant difference in the odds of reoperation or overall complications. Nevertheless, there were significantly more events of postoperative anemia in this high INR patient group.
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spelling pubmed-75551952020-10-19 Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio Kain, Michael S. Saper, David Lybrand, Kyle Bramlett, Kasey-Jean Tornetta III, Paul Althausen, Peter Garfi, John S. Willier III, Donald P. Niu, Ruijia Marcantonio, Andrew J. Geriatrics (Basel) Article In current clinical practice, orthopedic surgeons often delay the surgery intervention on geriatric hip fracture patients to optimize the international normalized ratio (INR), in order to decrease the risk of postoperative hematological complications. However, some evidence suggests that full reversal protocols may not be necessary, especially for patients with prior thromboembolic history. Our study aims to compare the surgical outcomes of patients with normal versus elevated INR values. We conducted a retrospective chart review on 217 patients who underwent surgeries on hip fractures at two academic trauma centers. We found that in our group (n = 124) of patients with an INR value of 1.5–3.0, there was only one reoperation for a hematoma, but there was a trend for more blood transfusions. There was no statistically significant difference in the odds of reoperation or overall complications. Nevertheless, there were significantly more events of postoperative anemia in this high INR patient group. MDPI 2020-07-15 /pmc/articles/PMC7555195/ /pubmed/32679667 http://dx.doi.org/10.3390/geriatrics5030043 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kain, Michael S.
Saper, David
Lybrand, Kyle
Bramlett, Kasey-Jean
Tornetta III, Paul
Althausen, Peter
Garfi, John S.
Willier III, Donald P.
Niu, Ruijia
Marcantonio, Andrew J.
Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio
title Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio
title_full Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio
title_fullStr Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio
title_full_unstemmed Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio
title_short Postoperative Complications of Hip Fractures Patients on Chronic Coumadin: A Comparison Based on Operative International Normalized Ratio
title_sort postoperative complications of hip fractures patients on chronic coumadin: a comparison based on operative international normalized ratio
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555195/
https://www.ncbi.nlm.nih.gov/pubmed/32679667
http://dx.doi.org/10.3390/geriatrics5030043
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