Cargando…

N-Acetylaspartylglutamate (NAAG) Pretreatment Reduces Hypoxic-Ischemic Brain Damage and Oxidative Stress in Neonatal Rats

N-acetylaspartylglutamate (NAAG), the most abundant peptide transmitter in the mammalian nervous system, activates mGluR3 at presynaptic sites, inhibiting the release of glutamate, and acts on mGluR3 on astrocytes, stimulating the release of neuroprotective growth factors (TGF-β). NAAG can also affe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bratek, Ewelina, Ziembowicz, Apolonia, Salinska, Elzbieta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555246/ https://www.ncbi.nlm.nih.gov/pubmed/32957477 http://dx.doi.org/10.3390/antiox9090877

Ejemplares similares

Group II Metabotropic Glutamate Receptors Reduce Apoptosis and Regulate BDNF and GDNF Levels in Hypoxic-Ischemic Injury in Neonatal Rats
por: Bratek-Gerej, Ewelina, et al.
Publicado: (2022)

Pretreatment with Group II Metabotropic Glutamate Receptor Agonist LY379268 Protects Neonatal Rat Brains from Oxidative Stress in an Experimental Model of Birth Asphyxia
por: Bratek, Ewelina, et al.
Publicado: (2018)

Pretreatment with mGluR2 or mGluR3 Agonists Reduces Apoptosis Induced by Hypoxia-Ischemia in Neonatal Rat Brains
por: Bratek - Gerej, Ewelina, et al.
Publicado: (2021)

The activation of group II metabotropic glutamate receptors protects neonatal rat brains from oxidative stress injury after hypoxia-ischemia
por: Bratek, Ewelina, et al.
Publicado: (2018)

The Mechanism of the Neuroprotective Effect of Kynurenic Acid in the Experimental Model of Neonatal Hypoxia–Ischemia: The Link to Oxidative Stress
por: Bratek-Gerej, Ewelina, et al.
Publicado: (2021)

Intracerebroventricular administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in inflammatory pain
por: Yamamoto, Tatsuo, et al.
Publicado: (2008)

Endogenous N-acetylaspartylglutamate (NAAG) inhibits synaptic plasticity/transmission in the amygdala in a mouse inflammatory pain model
por: Adedoyin, Mary O, et al.
Publicado: (2010)

Hyperbaric oxygen and hyperbaric air treatment result in comparable neuronal death reduction and improved behavioral outcome after transient forebrain ischemia in the gerbil
por: Malek, Michal, et al.
Publicado: (2012)

Dendritic Localization and Exocytosis of NAAG in the Rat Hippocampus
por: Nordengen, K, et al.
Publicado: (2020)

The regulatory role of NAAG-mGluR3 signaling on cortical synaptic plasticity after hypoxic ischemia
por: Li, Kexin, et al.
Publicado: (2022)

Gallic acid inhibits neuroinflammation and reduces neonatal hypoxic-ischemic brain damages
por: Dong, Xiangjun, et al.
Publicado: (2022)

NAA and NAAG variation in neuronal activation during visual stimulation
por: Castellano, G., et al.
Publicado: (2012)

Proton magnetic resonance spectroscopy reveals significant decline in the contents of N-acetylaspartylglutamate in the hippocampus of aged healthy subjects
por: Chang, Ruiting, et al.
Publicado: (2016)

NAAG peptidase inhibition in the periaqueductal gray and rostral ventromedial medulla reduces flinching in the formalin model of inflammation
por: Yamada, Toshihiko, et al.
Publicado: (2012)

Pretreatment with Human Chorionic Gonadotropin Protects the Neonatal Brain against the Effects of Hypoxic-Ischemic Injury
por: Movsas, Tammy Z., et al.
Publicado: (2017)

A role for the locus coeruleus in the analgesic efficacy of N-acetylaspartylglutamate peptidase (GCPII) inhibitors ZJ43 and 2-PMPA
por: Nonaka, Takahiro, et al.
Publicado: (2017)

Dihydroartemisinin attenuates hypoxic-ischemic brain damage in neonatal rats by inhibiting oxidative stress
por: Xiong, Qian, et al.
Publicado: (2022)

Peptidome analysis of cerebrospinal fluid in neonates with hypoxic-ischemic brain damage
por: Hou, Xuewen, et al.
Publicado: (2020)

Resatorvid protects against hypoxic-ischemic brain damage in neonatal rats
por: Jiang, Li-Jun, et al.
Publicado: (2020)

Neuroprotective Mechanism of Icariin on Hypoxic Ischemic Brain Damage in Neonatal Mice
por: Wang, Mengxia, et al.
Publicado: (2022)

Hypothermia Modulates Cytokine Responses After Neonatal Rat Hypoxic-Ischemic Injury and Reduces Brain Damage
por: Yuan, Xiangpeng, et al.
Publicado: (2014)

NaAg(2)Mo(3)O(9)AsO(4)
por: Hamza, Hamadi, et al.
Publicado: (2010)

Attenuation of oxidative damage by targeting mitochondrial complex I in neonatal hypoxic-ischemic brain injury
por: Kim, Minso, et al.
Publicado: (2018)

Comparison of the Effects of Citicoline and Piracetam on Hypoxic-ischemic Brain Damage in Neonatal Rabbits
por: EBRAHIMI, Sedigheh, et al.
Publicado: (2022)

Research advances in the role of endogenous neurogenesis on neonatal hypoxic-ischemic brain damage
por: Chen, Andi, et al.
Publicado: (2022)

Sodium Pyruvate Reduced Hypoxic-Ischemic Injury to Neonatal Rat Brain
por: Pan, Rui, et al.
Publicado: (2012)

Extracellular N-acetylaspartylglutamate released in the nucleus accumbens modulates the pain sensation: Analysis using a microdialysis/mass spectrometry integrated system
por: Watanabe, Moe, et al.
Publicado: (2018)

Hypoxic Roadmap of Glioblastoma—Learning about Directions and Distances in the Brain Tumor Environment
por: Bronisz, Agnieszka, et al.
Publicado: (2020)

Estrogen inhibits lipid peroxidation after hypoxic-ischemic brain damage in neonatal rats★
por: Zhu, Hui, et al.
Publicado: (2012)

Circular RNA expression profiles in neonatal rats following hypoxic-ischemic brain damage
por: Jiang, Li, et al.
Publicado: (2019)

Marine Compound Xyloketal B Reduces Neonatal Hypoxic-Ischemic Brain Injury
por: Xiao, Ai-Jiao, et al.
Publicado: (2014)

Azithromycin Reduces Inflammation-Amplified Hypoxic-Ischemic Brain Injury in Neonatal Rats
por: Barks, John D.E., et al.
Publicado: (2022)

Different antecedents and neonatal condition in neonatal arterial ischemic stroke and hypoxic‐ischemic neonatal encephalopathy
por: Lambicchi, Laura, et al.
Publicado: (2021)

Human Cord Blood for the Hypoxic-Ischemic Neonate
por: Carroll, James
Publicado: (2012)

Language in Children with Neonatal Hypoxic-Ischemic Encephalopathy
por: Martinez, Chenia, et al.
Publicado: (2014)

Neuroprotection of lamotrigine on hypoxic-ischemic brain damage in neonatal rats: Relations to administration time and doses
por: Yi, Yong-Hong, et al.
Publicado: (2008)

New Insights into Mechanisms of Ferroptosis Associated with Immune Infiltration in Neonatal Hypoxic-Ischemic Brain Damage
por: Li, Shangbin, et al.
Publicado: (2022)

Telomerase reverse transcriptase promotes angiogenesis in neonatal rats after hypoxic-ischemic brain damage
por: Li, Jiao, et al.
Publicado: (2022)

Mechanism and Treatment Related to Oxidative Stress in Neonatal Hypoxic-Ischemic Encephalopathy
por: Qin, Xingping, et al.
Publicado: (2019)

Neuroprotection of N-benzyl Eicosapentaenamide in Neonatal Mice Following Hypoxic–Ischemic Brain Injury
por: Jiao, Mengya, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_iedks3id30otkgd4b354t6kqn3