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Evaluation of the Usefulness of CO-RADS for Chest CT in Patients Suspected of Having COVID-19

The purpose of this study was to use the Coronavirus Disease 2019 (COVID-19) Reporting and Data System (CO-RADS) to evaluate the chest computed tomography (CT) images of patients suspected of having COVID-19, and to investigate its diagnostic performance and interobserver agreement. The Dutch Radiol...

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Autores principales: Fujioka, Tomoyuki, Takahashi, Marie, Mori, Mio, Tsuchiya, Junichi, Yamaga, Emi, Horii, Toshihiro, Yamada, Hirofumi, Kimura, Mizuki, Kimura, Koichiro, Kitazume, Yoshio, Kishino, Mitsuhiro, Tateishi, Ukihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555303/
https://www.ncbi.nlm.nih.gov/pubmed/32825060
http://dx.doi.org/10.3390/diagnostics10090608
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author Fujioka, Tomoyuki
Takahashi, Marie
Mori, Mio
Tsuchiya, Junichi
Yamaga, Emi
Horii, Toshihiro
Yamada, Hirofumi
Kimura, Mizuki
Kimura, Koichiro
Kitazume, Yoshio
Kishino, Mitsuhiro
Tateishi, Ukihide
author_facet Fujioka, Tomoyuki
Takahashi, Marie
Mori, Mio
Tsuchiya, Junichi
Yamaga, Emi
Horii, Toshihiro
Yamada, Hirofumi
Kimura, Mizuki
Kimura, Koichiro
Kitazume, Yoshio
Kishino, Mitsuhiro
Tateishi, Ukihide
author_sort Fujioka, Tomoyuki
collection PubMed
description The purpose of this study was to use the Coronavirus Disease 2019 (COVID-19) Reporting and Data System (CO-RADS) to evaluate the chest computed tomography (CT) images of patients suspected of having COVID-19, and to investigate its diagnostic performance and interobserver agreement. The Dutch Radiological Society developed CO-RADS as a diagnostic indicator for assessing suspicion of lung involvement of COVID-19 on a scale of 1 (very low) to 5 (very high). We investigated retrospectively 154 adult patients with clinically suspected COVID-19, between April and June 2020, who underwent chest CT and reverse transcription-polymerase chain reaction (RT-PCR). The patients’ average age was 61.3 years (range, 21–93), 101 were male, and 76 were RT-PCR positive. Using CO-RADS, four radiologists evaluated the chest CT images. Sensitivity, specificity, and area under the receiver operating characteristic curve (AUC) were calculated. Interobserver agreement was calculated using the intraclass correlation coefficient (ICC) by comparing the individual reader’s score to the median of the remaining three radiologists. The average sensitivity was 87.8% (range, 80.2–93.4%), specificity was 66.4% (range, 51.3–84.5%), and AUC was 0.859 (range, 0.847–0.881); there was no significant difference between the readers (p > 0.200). In 325 (52.8%) of 616 observations, there was absolute agreement among observers. The average ICC of readers was 0.840 (range, 0.800–0.874; p < 0.001). CO-RADS is a categorical taxonomic evaluation scheme for COVID-19 pneumonia, using chest CT images, that provides outstanding performance and from substantial to almost perfect interobserver agreement for predicting COVID-19.
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spelling pubmed-75553032020-10-19 Evaluation of the Usefulness of CO-RADS for Chest CT in Patients Suspected of Having COVID-19 Fujioka, Tomoyuki Takahashi, Marie Mori, Mio Tsuchiya, Junichi Yamaga, Emi Horii, Toshihiro Yamada, Hirofumi Kimura, Mizuki Kimura, Koichiro Kitazume, Yoshio Kishino, Mitsuhiro Tateishi, Ukihide Diagnostics (Basel) Article The purpose of this study was to use the Coronavirus Disease 2019 (COVID-19) Reporting and Data System (CO-RADS) to evaluate the chest computed tomography (CT) images of patients suspected of having COVID-19, and to investigate its diagnostic performance and interobserver agreement. The Dutch Radiological Society developed CO-RADS as a diagnostic indicator for assessing suspicion of lung involvement of COVID-19 on a scale of 1 (very low) to 5 (very high). We investigated retrospectively 154 adult patients with clinically suspected COVID-19, between April and June 2020, who underwent chest CT and reverse transcription-polymerase chain reaction (RT-PCR). The patients’ average age was 61.3 years (range, 21–93), 101 were male, and 76 were RT-PCR positive. Using CO-RADS, four radiologists evaluated the chest CT images. Sensitivity, specificity, and area under the receiver operating characteristic curve (AUC) were calculated. Interobserver agreement was calculated using the intraclass correlation coefficient (ICC) by comparing the individual reader’s score to the median of the remaining three radiologists. The average sensitivity was 87.8% (range, 80.2–93.4%), specificity was 66.4% (range, 51.3–84.5%), and AUC was 0.859 (range, 0.847–0.881); there was no significant difference between the readers (p > 0.200). In 325 (52.8%) of 616 observations, there was absolute agreement among observers. The average ICC of readers was 0.840 (range, 0.800–0.874; p < 0.001). CO-RADS is a categorical taxonomic evaluation scheme for COVID-19 pneumonia, using chest CT images, that provides outstanding performance and from substantial to almost perfect interobserver agreement for predicting COVID-19. MDPI 2020-08-19 /pmc/articles/PMC7555303/ /pubmed/32825060 http://dx.doi.org/10.3390/diagnostics10090608 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fujioka, Tomoyuki
Takahashi, Marie
Mori, Mio
Tsuchiya, Junichi
Yamaga, Emi
Horii, Toshihiro
Yamada, Hirofumi
Kimura, Mizuki
Kimura, Koichiro
Kitazume, Yoshio
Kishino, Mitsuhiro
Tateishi, Ukihide
Evaluation of the Usefulness of CO-RADS for Chest CT in Patients Suspected of Having COVID-19
title Evaluation of the Usefulness of CO-RADS for Chest CT in Patients Suspected of Having COVID-19
title_full Evaluation of the Usefulness of CO-RADS for Chest CT in Patients Suspected of Having COVID-19
title_fullStr Evaluation of the Usefulness of CO-RADS for Chest CT in Patients Suspected of Having COVID-19
title_full_unstemmed Evaluation of the Usefulness of CO-RADS for Chest CT in Patients Suspected of Having COVID-19
title_short Evaluation of the Usefulness of CO-RADS for Chest CT in Patients Suspected of Having COVID-19
title_sort evaluation of the usefulness of co-rads for chest ct in patients suspected of having covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555303/
https://www.ncbi.nlm.nih.gov/pubmed/32825060
http://dx.doi.org/10.3390/diagnostics10090608
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