Cargando…

1,4-Disubstituted-1,2,3-Triazole Compounds Induce Ultrastructural Alterations in Leishmania amazonensis Promastigote: An in Vitro Antileishmanial and in Silico Pharmacokinetic Study

The current standard treatment for leishmaniasis has remained the same for over 100 years, despite inducing several adverse effects and increasing cases of resistance. In this study we evaluated the in vitro antileishmanial activity of 1,4-disubstituted-1,2,3 triazole compounds and carried out in si...

Descripción completa

Detalles Bibliográficos
Autores principales: Almeida-Souza, Fernando, da Silva, Verônica Diniz, Silva, Gabriel Xavier, Taniwaki, Noemi Nosomi, Hardoim, Daiana de Jesus, Buarque, Camilla Djenne, Abreu-Silva, Ana Lucia, Calabrese, Kátia da Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555349/
https://www.ncbi.nlm.nih.gov/pubmed/32961842
http://dx.doi.org/10.3390/ijms21186839