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1,4-Disubstituted-1,2,3-Triazole Compounds Induce Ultrastructural Alterations in Leishmania amazonensis Promastigote: An in Vitro Antileishmanial and in Silico Pharmacokinetic Study
The current standard treatment for leishmaniasis has remained the same for over 100 years, despite inducing several adverse effects and increasing cases of resistance. In this study we evaluated the in vitro antileishmanial activity of 1,4-disubstituted-1,2,3 triazole compounds and carried out in si...
Autores principales: | Almeida-Souza, Fernando, da Silva, Verônica Diniz, Silva, Gabriel Xavier, Taniwaki, Noemi Nosomi, Hardoim, Daiana de Jesus, Buarque, Camilla Djenne, Abreu-Silva, Ana Lucia, Calabrese, Kátia da Silva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555349/ https://www.ncbi.nlm.nih.gov/pubmed/32961842 http://dx.doi.org/10.3390/ijms21186839 |
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