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The mitotic protein NuMA plays a spindle-independent role in nuclear formation and mechanics

Eukaryotic cells typically form a single, round nucleus after mitosis, and failures to do so can compromise genomic integrity. How mammalian cells form such a nucleus remains incompletely understood. NuMA is a spindle protein whose disruption results in nuclear fragmentation. What role NuMA plays in...

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Detalles Bibliográficos
Autores principales:	Serra-Marques, Andrea, Houtekamer, Ronja, Hintzen, Dorine, Canty, John T., Yildiz, Ahmet, Dumont, Sophie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555356/ https://www.ncbi.nlm.nih.gov/pubmed/33044554 http://dx.doi.org/10.1083/jcb.202004202

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