Influence of Oxidative Stress Biomarkers and Genetic Polymorphisms on the Clinical Severity of Hydroxyurea-Free Senegalese Children with Sickle Cell Anemia

Oxidative stress would play a role in the pathophysiology of sickle cell anemia (SCA). We tested the impact of common SCA genetic modifiers (alpha-thalassemia, G6PD deficiency, HbF quantitative trait loci; QTL) and pro/antioxidant genes polymorphisms (SOD2 rs4880, XO rs207454, MPO rs2333227) on oxid...

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Detalles Bibliográficos
Autores principales: Gueye Tall, Fatou, Martin, Cyril, Ndour, El hadji Malick, Faes, Camille, Déme Ly, Indou, Pialoux, Vincent, Connes, Philippe, Gueye, Papa Madieye, Ndiaye Diallo, Rokhaya, Renoux, Céline, Diagne, Ibrahima, Diop, Pape Amadou, Cissé, Aynina, Sall, Philomène Lopez, Joly, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555380/
https://www.ncbi.nlm.nih.gov/pubmed/32937882
http://dx.doi.org/10.3390/antiox9090863

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