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Ilimaquinone Induces Apoptosis and Autophagy in Human Oral Squamous Cell Carcinoma Cells

In this study, the anti-tumor activity of ilimaquinone (IQ), a sesquiterpene quinone isolated from marine sponge Halichondria sp., in oral squamous cell carcinoma (OSCC) cells, was investigated. IQ suppressed the viability of the OSCC cell lines SCC4 and SCC2095 with IC(50) values of 7.5 and 8.5 μM,...

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Detalles Bibliográficos
Autores principales: Lin, Cheng-Wen, Bai, Li-Yuan, Su, Jui-Hsin, Chiu, Chang-Fang, Lin, Wei-Yu, Huang, Wei-Ting, Shih, Ming-Cheng, Huang, Yu-Ting, Hu, Jing-Lan, Weng, Jing-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555415/
https://www.ncbi.nlm.nih.gov/pubmed/32825464
http://dx.doi.org/10.3390/biomedicines8090296