Cargando…

Engineered Fragments of the PSMA-Specific 5D3 Antibody and Their Functional Characterization

Prostate-Specific Membrane Antigen (PSMA) is an established biomarker for the imaging and experimental therapy of prostate cancer (PCa), as it is strongly upregulated in high-grade primary, androgen-independent, and metastatic lesions. Here, we report on the development and functional characterizati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Novakova, Zora, Belousova, Nikola, Foss, Catherine A., Havlinova, Barbora, Gresova, Marketa, Das, Gargi, Lisok, Ala, Prada, Adam, Barinkova, Marketa, Hubalek, Martin, Pomper, Martin G., Barinka, Cyril
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555429/ https://www.ncbi.nlm.nih.gov/pubmed/32932591 http://dx.doi.org/10.3390/ijms21186672

Ejemplares similares

Heterologous expression and purification of recombinant human protoporphyrinogen oxidase IX: A comparative study
por: Novakova, Zora, et al.
Publicado: (2021)

Human histone deacetylase 6 shows strong preference for tubulin dimers over assembled microtubules
por: Skultetyova, Lubica, et al.
Publicado: (2017)

Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene
por: Novakova, Zora, et al.
Publicado: (2022)

Heterobivalent Agents Targeting PSMA and Integrin-α(v)β(3)
por: Shallal, Hassan M., et al.
Publicado: (2014)

A Modular Strategy to Prepare Multivalent Inhibitors of Prostate-Specific Membrane Antigen (PSMA)
por: Banerjee, Sangeeta Ray, et al.
Publicado: (2011)

Prostate-specific membrane antigen (PSMA)-targeted photodynamic therapy enhances the delivery of PSMA-targeted magnetic nanoparticles to PSMA-expressing prostate tumors
por: Ngen, Ethel J., et al.
Publicado: (2021)

Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer
por: Ptacek, Jakub, et al.
Publicado: (2020)

Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6)
por: Motlová, Lucia, et al.
Publicado: (2023)

A Series of PSMA-Targeted Near-Infrared Fluorescent Imaging Agents
por: Chen, Ying, et al.
Publicado: (2022)

An Evaluation of CXCR4 Targeting with PAMAM Dendrimer Conjugates for Oncologic Applications
por: Lesniak, Wojciech G., et al.
Publicado: (2022)

Preclinical Evaluation of a New Series of Albumin-Binding (177)Lu-Labeled PSMA-Based Low-Molecular-Weight Radiotherapeutics
por: Boinapally, Srikanth, et al.
Publicado: (2023)

Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells
por: Ptacek, Jakub, et al.
Publicado: (2023)

Enhancement of Radiotherapy with Human Mesenchymal Stem Cells Containing Gold Nanoparticles
por: Pullambhatla, Mrudula, et al.
Publicado: (2020)

Prostate-specific membrane antigen (PSMA) imaging: the past is prologue and the future is scintillating
por: Rowe, Steven P., et al.
Publicado: (2020)

Continuous Activity Assay for HDAC11 Enabling Reevaluation of HDAC Inhibitors
por: Kutil, Zsófia, et al.
Publicado: (2019)

A fully human CXCR4 antibody demonstrates diagnostic utility and therapeutic efficacy in solid tumor xenografts
por: Azad, Babak Behnam, et al.
Publicado: (2016)

System-level optimization in spectroscopic photoacoustic imaging of prostate cancer
por: Wu, Yixuan, et al.
Publicado: (2022)

Effect of Point-Spread Function Reconstruction for Indeterminate PSMA-RADS-3A Lesions on PSMA-Targeted PET Imaging of Men with Prostate Cancer
por: Khatri, Wajahat, et al.
Publicado: (2021)

Deep learning and radiomics framework for PSMA-RADS classification of prostate cancer on PSMA PET
por: Leung, Kevin H., et al.
Publicado: (2022)

A humanized antibody for imaging immune checkpoint ligand PD-L1 expression in tumors
por: Chatterjee, Samit, et al.
Publicado: (2016)

Thermal stabilisation of the short DNA duplexes by acridine-4-carboxamide derivatives
por: Kostelansky, Filip, et al.
Publicado: (2022)

A dextran-based probe for the targeted magnetic resonance imaging of tumours expressing prostate-specific membrane antigen
por: Liu, Guanshu, et al.
Publicado: (2017)

A side-by-side evaluation of [(18)F]FDOPA enantiomers for non-invasive detection of neuroendocrine tumors by positron emission tomography
por: Narayan, Athira, et al.
Publicado: (2019)

PSMA-targeted [(18)F]DCFPyL PET/CT-avid lesions in a patient with prostate cancer: Clinical decision-making informed by the PSMA-RADS interpretive framework
por: Reyes, Diane K., et al.
Publicado: (2019)

Development of prostate specific membrane antigen targeted ultrasound microbubbles using bioorthogonal chemistry
por: Zlitni, Aimen, et al.
Publicado: (2017)

Peptide-Based (68)Ga-PET Radiotracer for Imaging PD-L1 Expression in Cancer
por: De Silva, Ravindra A., et al.
Publicado: (2018)

Development of [(18)F]FPy-WL12 as a PD-L1 Specific PET Imaging Peptide
por: Lesniak, Wojciech G., et al.
Publicado: (2019)

Voltammetry as a Tool for Characterization of CdTe Quantum Dots
por: Sobrova, Pavlina, et al.
Publicado: (2013)

SUV(mean) on baseline [(18)F]PSMA-1007 PET and clinical parameters are associated with survival in prostate cancer patients scheduled for [(177)Lu]Lu-PSMA I&T
por: Hartrampf, Philipp E., et al.
Publicado: (2023)

A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging
por: Zhang, Jingming, et al.
Publicado: (2021)

Imaging CAR T cell therapy with PSMA-targeted positron emission tomography
por: Minn, Il, et al.
Publicado: (2019)

The Role of Cysteine Residues in Catalysis of Phosphoenolpyruvate Carboxykinase from Mycobacterium tuberculosis
por: Machová, Iva, et al.
Publicado: (2017)

Diagnosing small bowel carcinoid tumor in a patient with oligometastatic prostate cancer imaged with PSMA-Targeted [(18)F]DCFPyL PET/CT: Value of the PSMA-RADS-3D Designation
por: Shenderov, Eugene, et al.
Publicado: (2017)

Characterization of glutamate carboxypeptidase 2 orthologs in trematodes
por: Jedlickova, Lucie, et al.
Publicado: (2022)

A prostate-specific membrane antigen (PSMA)-targeted prodrug with a favorable in vivo toxicity profile
por: Boinapally, Srikanth, et al.
Publicado: (2021)

Phlebotomine sand fly survey in the Republic of Moldova: species composition, distribution and host preferences
por: Șuleșco, Tatiana, et al.
Publicado: (2021)

What Has Been Seen Cannot Be Unseen—Detecting Auxin In Vivo
por: Pařízková, Barbora, et al.
Publicado: (2017)

Identification of highly variable sequence fragments in unmapped reads for rapid bacterial genotyping
por: Nykrynova, Marketa, et al.
Publicado: (2022)

High Interobserver Agreement on PSMA PET/CT Even in the Absence of Clinical Data
por: Bundschuh, Ralph A., et al.
Publicado: (2023)

Targeted delivery of cytotoxic proteins to prostate cancer via conjugation to small molecule urea-based PSMA inhibitors
por: Rogers, O. C., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pnh67gd8c9me09j32rh81r2cu5