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Covalent protein display on Hepatitis B core-like particles in plants through the in vivo use of the SpyTag/SpyCatcher system
Virus-like particles (VLPs) can be used as nano-carriers and antigen-display systems in vaccine development and therapeutic applications. Conjugation of peptides or whole proteins to VLPs can be achieved using different methods such as the SpyTag/SpyCatcher system. Here we investigate the conjugatio...
Autores principales: | Peyret, Hadrien, Ponndorf, Daniel, Meshcheriakova, Yulia, Richardson, Jake, Lomonossoff, George P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555512/ https://www.ncbi.nlm.nih.gov/pubmed/33051543 http://dx.doi.org/10.1038/s41598-020-74105-w |
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