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A novel TRPM7/O-GlcNAc axis mediates tumour cell motility and metastasis by stabilising c-Myc and caveolin-1 in lung carcinoma
BACKGROUND: Calcium is an essential signal transduction element that has been associated with aggressive behaviours in several cancers. Cell motility is a prerequisite for metastasis, the major cause of lung cancer death, yet its association with calcium signalling and underlying regulatory axis rem...
Autores principales: | Luanpitpong, Sudjit, Rodboon, Napachai, Samart, Parinya, Vinayanuwattikun, Chanida, Klamkhlai, Siwaporn, Chanvorachote, Pithi, Rojanasakul, Yon, Issaragrisil, Surapol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555538/ https://www.ncbi.nlm.nih.gov/pubmed/32684624 http://dx.doi.org/10.1038/s41416-020-0991-7 |
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