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Adverse Effects of Methylglyoxal on Transcriptome and Metabolic Changes in Visceral Adipose Tissue in a Prediabetic Rat Model

Excessive methylglyoxal (MG) production contributes to metabolic and vascular changes by increasing inflammatory processes, disturbing regulatory mechanisms and exacerbating tissue dysfunction. MG accumulation in adipocytes leads to structural and functional changes. We used transcriptome analysis t...

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Detalles Bibliográficos
Autores principales: Hüttl, Martina, Markova, Irena, Miklankova, Denisa, Makovicky, Pavol, Pelikanova, Terezie, Šeda, Ondrej, Šedová, Lucie, Malinska, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555565/
https://www.ncbi.nlm.nih.gov/pubmed/32878255
http://dx.doi.org/10.3390/antiox9090803