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Flavonoids Restore Platinum Drug Sensitivity to Ovarian Carcinoma Cells in a Phospho-ERK1/2-Dependent Fashion

Ovarian cancer (OC) is the second most common type of gynecological malignancy; it has poor survival rates and is frequently (>75%) diagnosed at an advanced stage. Platinum-based chemotherapy, with, e.g., carboplatin, is the standard of care for OC, but toxicity and acquired resistance to therapy...

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Detalles Bibliográficos
Autores principales: Koren Carmi, Yifat, Mahmoud, Hatem, Khamaisi, Hazem, Adawi, Rina, Gopas, Jacob, Mahajna, Jamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555577/
https://www.ncbi.nlm.nih.gov/pubmed/32906729
http://dx.doi.org/10.3390/ijms21186533