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Flavonoids Restore Platinum Drug Sensitivity to Ovarian Carcinoma Cells in a Phospho-ERK1/2-Dependent Fashion
Ovarian cancer (OC) is the second most common type of gynecological malignancy; it has poor survival rates and is frequently (>75%) diagnosed at an advanced stage. Platinum-based chemotherapy, with, e.g., carboplatin, is the standard of care for OC, but toxicity and acquired resistance to therapy...
Autores principales: | Koren Carmi, Yifat, Mahmoud, Hatem, Khamaisi, Hazem, Adawi, Rina, Gopas, Jacob, Mahajna, Jamal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555577/ https://www.ncbi.nlm.nih.gov/pubmed/32906729 http://dx.doi.org/10.3390/ijms21186533 |
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