A Multi-Scale Computational Model of Excitotoxic Loss of Dopaminergic Cells in Parkinson's Disease

Parkinson's disease (PD) is a neurodegenerative disorder caused by loss of dopaminergic neurons in substantia nigra pars compacta (SNc). Although the exact cause of cell death is not clear, the hypothesis that metabolic deficiency is a key factor has been gaining attention in recent years. In t...

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Detalles Bibliográficos
Autores principales: Muddapu, Vignayanandam Ravindernath, Chakravarthy, V. Srinivasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555610/
https://www.ncbi.nlm.nih.gov/pubmed/33101001
http://dx.doi.org/10.3389/fninf.2020.00034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555610/
https://www.ncbi.nlm.nih.gov/pubmed/33101001
http://dx.doi.org/10.3389/fninf.2020.00034

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