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Phospholipase D1 and D2 Synergistically Regulate Thrombus Formation

Previously, we reported that phospholipase D1 (PLD1) and PLD2 inhibition by selective PLD1 and PLD2 inhibitors could prevent platelet aggregation in humans, but not in mice. Moreover, only the PLD1 inhibitor, but not PLD2 inhibitor, could effectively prevent thrombus formation in mice, indicating th...

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Detalles Bibliográficos
Autores principales: Lien, Li-Ming, Lu, Wan-Jung, Chen, Ting-Yu, Lee, Tzu-Yin, Wang, Hsueh-Hsiao, Peng, Hsien-Yu, Chen, Ray-Jade, Lin, Kuan-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555624/
https://www.ncbi.nlm.nih.gov/pubmed/32971863
http://dx.doi.org/10.3390/ijms21186954