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Nasal Immunization with the C-Terminal Domain of Bcla3 Induced Specific IgG Production and Attenuated Disease Symptoms in Mice Infected with Clostridioides difficile Spores

Clostridioides difficile is a Gram-positive, spore-forming bacterium that causes a severe intestinal infection. Spores of this pathogen enter in the human body through the oral route, interact with intestinal epithelial cells and persist in the gut. Once germinated, the vegetative cells colonize the...

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Detalles Bibliográficos
Autores principales: Maia, Ana Raquel, Reyes-Ramírez, Rodrigo, Pizarro-Guajardo, Marjorie, Saggese, Anella, Ricca, Ezio, Baccigalupi, Loredana, Paredes-Sabja, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555657/
https://www.ncbi.nlm.nih.gov/pubmed/32933117
http://dx.doi.org/10.3390/ijms21186696

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