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Nasal Immunization with the C-Terminal Domain of Bcla3 Induced Specific IgG Production and Attenuated Disease Symptoms in Mice Infected with Clostridioides difficile Spores
Clostridioides difficile is a Gram-positive, spore-forming bacterium that causes a severe intestinal infection. Spores of this pathogen enter in the human body through the oral route, interact with intestinal epithelial cells and persist in the gut. Once germinated, the vegetative cells colonize the...
Autores principales: | Maia, Ana Raquel, Reyes-Ramírez, Rodrigo, Pizarro-Guajardo, Marjorie, Saggese, Anella, Ricca, Ezio, Baccigalupi, Loredana, Paredes-Sabja, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555657/ https://www.ncbi.nlm.nih.gov/pubmed/32933117 http://dx.doi.org/10.3390/ijms21186696 |
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