Polyfunctional Fc Dependent Activity of Antibodies to Native Trimeric Envelope in HIV Elite Controllers

Antibody dependent (AD) functions such as AD cellular cytotoxicity (ADCC) were associated with lower viral load (VL) in untreated HIV progressors and protection from HIV infection in the modestly protective RV144 HIV vaccine trial. Target cells used to measure ADCC, AD complement deposition (ADCD),...

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Detalles Bibliográficos
Autores principales: Kant, Sanket, Zhang, Ningyu, Barbé, Alexandre, Routy, Jean-Pierre, Tremblay, Cécile, Thomas, Réjean, Szabo, Jason, Côté, Pierre, Trottier, Benoit, LeBlanc, Roger, Rouleau, Danielle, Harris, Marianne, Dupuy, Franck P., Bernard, Nicole F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555699/
https://www.ncbi.nlm.nih.gov/pubmed/33101312
http://dx.doi.org/10.3389/fimmu.2020.583820

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