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Ligation-Mediated Polymerase Chain Reaction Detection of 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine and 5-Hydroxycytosine at the Codon 176 of the p53 Gene of Hepatitis C-Associated Hepatocellular Carcinoma Patients
Molecular mechanisms underlying Hepatitis C virus (HCV)-associated hepatocellular carcinoma (HCC) pathogenesis are still unclear. Therefore, we analyzed the levels of 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) and other oxidative lesions at codon 176 of the p53 gene, as well as the generation of...
Autores principales: | Galli, Andrea, Munnia, Armelle, Cellai, Filippo, Tarocchi, Mirko, Ceni, Elisabetta, van Schooten, Frederik Jan, Godschalk, Roger, Giese, Roger W., Peluso, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555735/ https://www.ncbi.nlm.nih.gov/pubmed/32942546 http://dx.doi.org/10.3390/ijms21186753 |
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