Cargando…

Gene Expression Signature of Acquired Chemoresistance in Neuroblastoma Cells

Drug resistance of childhood cancer neuroblastoma is a serious clinical problem. Patients with relapsed disease have a poor prognosis despite intense treatment. In the present study, we aimed to identify chemoresistance gene expression signatures in vincristine resistant neuroblastoma cells. We foun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jemaà, Mohamed, Sime, Wondossen, Abassi, Yasmin, Lasorsa, Vito Alessandro, Bonne Køhler, Julie, Michaelis, Martin, Cinatl, Jindrich, Capasso, Mario, Massoumi, Ramin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555742/ https://www.ncbi.nlm.nih.gov/pubmed/32948088 http://dx.doi.org/10.3390/ijms21186811

Ejemplares similares

Discovery of epi-Enprioline as a Novel Drug for the Treatment of Vincristine Resistant Neuroblastoma
por: Sime, Wondossen, et al.
Publicado: (2020)

BAP1 induces cell death via interaction with 14-3-3 in neuroblastoma
por: Sime, Wondossen, et al.
Publicado: (2018)

Inhibition of mitotic kinase Mps1 promotes cell death in neuroblastoma
por: Simon Serrano, Sonia, et al.
Publicado: (2020)

Single-cell transcriptomics of neuroblastoma identifies chemoresistance-associated genes and pathways
por: Avitabile, Marianna, et al.
Publicado: (2022)

Chemoresistance acquisition induces a global shift of expression of aniogenesis-associated genes and increased pro-angogenic activity in neuroblastoma cells
por: Michaelis, Martin, et al.
Publicado: (2009)

Chemoresistance induces enhanced adhesion and transendothelial penetration of neuroblastoma cells by down-regulating NCAM surface expression
por: Blaheta, Roman A, et al.
Publicado: (2006)

Reversine inhibits Colon Carcinoma Cell Migration by Targeting JNK1
por: Jemaà, Mohamed, et al.
Publicado: (2018)

Drug-adapted cancer cell lines as preclinical models of acquired resistance
por: Michaelis, Martin, et al.
Publicado: (2019)

A Targeted Gene Panel for Circulating Tumor DNA Sequencing in Neuroblastoma
por: Cimmino, Flora, et al.
Publicado: (2020)

Effects of YM155 on survivin levels and viability in neuroblastoma cells with acquired drug resistance
por: Voges, Yvonne, et al.
Publicado: (2016)

NLK-mediated phosphorylation of HDAC1 negatively regulates Wnt signaling
por: Masoumi, Katarzyna Chmielarska, et al.
Publicado: (2017)

Novel Cyclophilin Inhibitor Decreases Cell Proliferation and Tumor Growth in Models of Hepatocellular Carcinoma
por: Simón Serrano, Sonia, et al.
Publicado: (2021)

CYLD and SUMO in neuroblastoma therapy
por: Masoumi, Katarzyna Chmielarska, et al.
Publicado: (2016)

Integrin α10-Antibodies Reduce Glioblastoma Tumor Growth and Cell Migration
por: Masoumi, Katarzyna Chmielarska, et al.
Publicado: (2021)

Aurora Kinases as Targets in Drug-Resistant Neuroblastoma Cells
por: Michaelis, Martin, et al.
Publicado: (2014)

BAG3 Overexpression and Cytoprotective Autophagy Mediate Apoptosis Resistance in Chemoresistant Breast Cancer Cells
por: Das, Chandan Kanta, et al.
Publicado: (2018)

CFDP1 is a neuroblastoma susceptibility gene that regulates transcription factors of the noradrenergic cell identity
por: Formicola, Daniela, et al.
Publicado: (2022)

Testing of the Survivin Suppressant YM155 in a Large Panel of Drug-Resistant Neuroblastoma Cell Lines
por: Michaelis, Martin, et al.
Publicado: (2020)

ABCB1 as predominant resistance mechanism in cells with acquired SNS-032 resistance
por: Löschmann, Nadine, et al.
Publicado: (2016)

Functional characterization of full-length BARD1 strengthens its role as a tumor suppressor in neuroblastoma
por: Cimmino, Flora, et al.
Publicado: (2020)

Association of PARP1 polymorphisms with response to chemotherapy in patients with high‐risk neuroblastoma
por: Avitabile, Marianna, et al.
Publicado: (2020)

ERBB and P‐glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P‐glycoprotein
por: Rösch, Lisa, et al.
Publicado: (2022)

19p loss is significantly enriched in older age neuroblastoma patients and correlates with poor prognosis
por: Lasorsa, Vito Alessandro, et al.
Publicado: (2020)

Autophagy is associated with chemoresistance in neuroblastoma
por: Belounis, Assila, et al.
Publicado: (2016)

A comprehensive characterization of rare mitochondrial DNA variants in neuroblastoma
por: Calabrese, Francesco Maria, et al.
Publicado: (2016)

Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (−)-Gossypol (AT-101)
por: Mani, Jens, et al.
Publicado: (2015)

FGFR1 is a potential therapeutic target in neuroblastoma
por: Cimmino, Flora, et al.
Publicado: (2022)

Association between acquired resistance to PLX4032 (vemurafenib) and ATP-binding cassette transporter expression
por: Michaelis, Martin, et al.
Publicado: (2014)

Kinome multigenic panel identified novel druggable EPHB4‐V871I somatic variant in high‐risk neuroblastoma
por: Andolfo, Immacolata, et al.
Publicado: (2020)

Effects of flavonoid-induced oxidative stress on anti-H5N1 influenza a virus activity exerted by baicalein and biochanin A
por: Michaelis, Martin, et al.
Publicado: (2014)

Investigation of the influence of EPs(®) 7630, a herbal drug preparation from Pelargonium sidoides, on replication of a broad panel of respiratory viruses
por: Michaelis, Martin, et al.
Publicado: (2011)

YM155-Adapted Cancer Cell Lines Reveal Drug-Induced Heterogeneity and Enable the Identification of Biomarker Candidates for the Acquired Resistance Setting
por: Michaelis, Martin, et al.
Publicado: (2020)

An 18 gene expression-based score classifier predicts the clinical outcome in stage 4 neuroblastoma
por: Formicola, Daniela, et al.
Publicado: (2016)

The small molecule inhibitor YK-4-279 disrupts mitotic progression of neuroblastoma cells, overcomes drug resistance and synergizes with inhibitors of mitosis
por: Kollareddy, Madhu, et al.
Publicado: (2017)

Identification of miRNAs contributing to neuroblastoma chemoresistance
por: Ayers, Duncan, et al.
Publicado: (2015)

Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents
por: Michaelis, M, et al.
Publicado: (2012)

Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen
por: Michaelis, Martin, et al.
Publicado: (2015)

ABCG2 impairs the activity of the aurora kinase inhibitor tozasertib but not of alisertib
por: Michaelis, Martin, et al.
Publicado: (2015)

Potential Role of miRNAs in the Acquisition of Chemoresistance in Neuroblastoma
por: Marengo, Barbara, et al.
Publicado: (2021)

Metallothionein-3 promotes cisplatin chemoresistance remodelling in neuroblastoma
por: Rodrigo, Miguel Angel Merlos, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6lis16d6luj78com7m0rog30s7