Cargando…
Targeting Molecular Mechanism of Vascular Smooth Muscle Senescence Induced by Angiotensin II, A Potential Therapy via Senolytics and Senomorphics
Cardiovascular disease (CVD) is a prevalent issue in the global aging population. Premature vascular aging such as elevated arterial stiffness appears to be a major risk factor for CVD. Vascular smooth muscle cells (VSMCs) are one of the essential parts of arterial pathology and prone to stress-indu...
Autores principales: | Okuno, Keisuke, Cicalese, Stephanie, Elliott, Katherine J., Kawai, Tatsuo, Hashimoto, Tomoki, Eguchi, Satoru |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555774/ https://www.ncbi.nlm.nih.gov/pubmed/32916794 http://dx.doi.org/10.3390/ijms21186579 |
Ejemplares similares
-
78 kDa Glucose-Regulated Protein Attenuates Protein Aggregation and Monocyte Adhesion Induced by Angiotensin II in Vascular Cells
por: Cicalese, Stephanie, et al.
Publicado: (2020) -
Endoplasmic Reticulum Chemical Chaperone 3‐Hydroxy‐2‐Naphthoic Acid Reduces Angiotensin II‐Induced Vascular Remodeling and Hypertension In Vivo and Protein Synthesis In Vitro
por: Cicalese, Stephanie, et al.
Publicado: (2022) -
Involvement of Senescence and Mitochondrial Fission in Endothelial Cell Pro-Inflammatory Phenotype Induced by Angiotensin II
por: Miyao, Masashi, et al.
Publicado: (2020) -
Nutritional senolytics and senomorphics: Implications to immune cells metabolism and aging – from theory to practice
por: Luís, Carla, et al.
Publicado: (2022) -
Senolytic and senomorphic secondary metabolites as therapeutic agents in Drosophila melanogaster models of Parkinson’s disease
por: Miller, Sean J., et al.
Publicado: (2023)