Cataract-Associated New Mutants S175G/H181Q of βΒ2-Crystallin and P24S/S31G of γD-Crystallin Are Involved in Protein Aggregation by Structural Changes

β/γ-Crystallins, the main structural protein in human lenses, have highly stable structure for keeping the lens transparent. Their mutations have been linked to cataracts. In this study, we identified 10 new mutations of β/γ-crystallins in lens proteomic dataset of cataract patients using bioinforma...

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Detalles Bibliográficos
Autores principales: Song, In-Kang, Na, Seungjin, Paek, Eunok, Lee, Kong-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555777/
https://www.ncbi.nlm.nih.gov/pubmed/32899552
http://dx.doi.org/10.3390/ijms21186504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555777/
https://www.ncbi.nlm.nih.gov/pubmed/32899552
http://dx.doi.org/10.3390/ijms21186504

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