Cargando…

Prevention of Rat Intestinal Injury with a Drug Combination of Melatonin and Misoprostol

A healthy intestinal barrier prevents uptake of allergens and toxins, whereas intestinal permeability increases following chemotherapy and in many gastrointestinal and systemic diseases and disorders. Currently, there are no approved drugs that target and repair the intestinal epithelial barrier whi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dahlgren, David, Cano-Cebrián, Maria-José, Hellström, Per M., Wanders, Alkwin, Sjöblom, Markus, Lennernäs, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555796/ https://www.ncbi.nlm.nih.gov/pubmed/32942716 http://dx.doi.org/10.3390/ijms21186771

Ejemplares similares

Protective Effects of Melatonin and Misoprostol against Experimentally Induced Increases in Intestinal Permeability in Rats
por: Peters, Karsten, et al.
Publicado: (2022)

Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies
por: Dahlgren, David, et al.
Publicado: (2021)

Chemotherapeutics Combined with Luminal Irritants: Effects on Small-Intestinal Mannitol Permeability and Villus Length in Rats
por: Cano-Cebrián, Maria-José, et al.
Publicado: (2022)

Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat
por: Dahlgren, David, et al.
Publicado: (2020)

Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats
por: Peters, Karsten, et al.
Publicado: (2021)

Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats
por: Dahlgren, David, et al.
Publicado: (2021)

Evaluation and validation of chemotherapy‐specific diarrhoea and histopathology in rats
por: Dahlgren, David, et al.
Publicado: (2022)

The In Vivo Effect of Transcellular Permeation Enhancers on the Intestinal Permeability of Two Peptide Drugs Enalaprilat and Hexarelin
por: Dahlgren, David, et al.
Publicado: (2020)

The progression of doxorubicin-induced intestinal mucositis in rats
por: Kullenberg, F., et al.
Publicado: (2022)

Intestinal Permeability and Drug Absorption: Predictive Experimental, Computational and In Vivo Approaches
por: Dahlgren, David, et al.
Publicado: (2019)

Intestinal absorption of BCS class II drugs administered as nanoparticles: A review based on in vivo data from intestinal perfusion models
por: Dahlgren, David, et al.
Publicado: (2020)

Antibody-Drug Conjugates and Targeted Treatment Strategies for Hepatocellular Carcinoma: A Drug-Delivery Perspective
por: Dahlgren, David, et al.
Publicado: (2020)

Hypotonicity-Induced Increase in Duodenal Mucosal Permeability Is Regulated by Cholinergic Receptors in Rats
por: Dahlgren, David, et al.
Publicado: (2022)

Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity
por: Holmbäck, Ulf, et al.
Publicado: (2020)

Exacerbation of Celecoxib-Induced Renal Injury by Concomitant Administration of Misoprostol in Rats
por: Cooper, Dustin L., et al.
Publicado: (2014)

Effects of α(2)-adrenoceptor stimulation on luminal alkalinisation and net fluid flux in rat duodenum
por: Nylander, Olof, et al.
Publicado: (2022)

A Case of Pancreatic Ductal Adenocarcinoma Arising From Atypical Flat Lesions
por: Franklin, Oskar, et al.
Publicado: (2020)

Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival
por: Nyman, Sofi Sennefelt, et al.
Publicado: (2022)

Efficacy of Rectal Misoprostol for Prevention of Postpartum Hemorrhage
por: Mirteimouri, Masoumeh, et al.
Publicado: (2013)

Melatonin in preservation solutions prevents ischemic injury in rat kidneys
por: Coskun, Abdurrahman, et al.
Publicado: (2022)

A huge retroperitoneal cyst with a rare clinical presentation
por: Alqaisi, Hayder, et al.
Publicado: (2022)

Mifepristone and Misoprostol vs Misoprostol Alone in Second Trimester Termination of Pregnancy
por: Shah, Deepa, et al.
Publicado: (2018)

Foley catheter plus misoprostol versus misoprostol alone for labor induction
por: Elpo, Jhonathan Alcides, et al.
Publicado: (2023)

Diminished DEFA6 Expression in Paneth Cells Is Associated with Necrotizing Enterocolitis
por: Markasz, Laszlo, et al.
Publicado: (2018)

Role of Combination OF Mifepristone and Misoprostol Verses Misoprostol alone in Induction of Labour in Late Intrauterin Fetal Death: A Prospective Study
por: Panda, Subrat, et al.
Publicado: (2013)

Safety and Efficacy of Misoprostol versus Oxytocin for the Prevention of Postpartum Hemorrhage
por: Rajaei, Minoo, et al.
Publicado: (2014)

Misoprostol Alone or in Combination with Methotrexate for Termination of Pregnancy at First Trimester
por: Vahid Roudsari, Fatemeh, et al.
Publicado: (2010)

An Infection-enhanced Oncolytic Adenovirus Secreting H. pylori Neutrophil-activating Protein with Therapeutic Effects on Neuroendocrine Tumors
por: Ramachandran, Mohanraj, et al.
Publicado: (2013)

Medical termination for pregnancy in early first trimester (≤ 63 days) using combination of mifepristone and misoprostol or misoprostol alone: a systematic review
por: Abubeker, Ferid A., et al.
Publicado: (2020)

Sublingual misoprostol vs. oral misoprostol solution for induction of labor: A retrospective study
por: Amini, Mahdi, et al.
Publicado: (2022)

Prophylactic supplement with melatonin prevented the brain injury after cardiac arrest in rats
por: Hu, Yanan, et al.
Publicado: (2023)

Labor induction with combined low-dose oral misoprostol and Foley catheter vs oral misoprostol alone at term gestation—a randomized study
por: Anjali, et al.
Publicado: (2022)

Combination Antioxidant Effect of Erythropoietin and Melatonin on Renal Ischemia-Reperfusion Injury in Rats
por: Ahmadiasl, Nasser, et al.
Publicado: (2013)

Impact of combined ischemic preconditioning and melatonin on renal ischemia-reperfusion injury in rats
por: Abdel-Razek, Hesham AD, et al.
Publicado: (2023)

Modeling maternal mortality in Bangladesh: the role of misoprostol in postpartum hemorrhage prevention
por: Prata, Ndola, et al.
Publicado: (2014)

Optimal dose of misoprostol combined with oxytocin for preventing postpartum hemorrhage in cesarean section: A randomised controlled trial
por: Sringamwong, Wirawan, et al.
Publicado: (2022)

The Impact of α-Adrenoceptors in the Regulation of the Hypotonicity-Induced Increase in Duodenal Mucosal Permeability In Vivo
por: Sedin, John, et al.
Publicado: (2021)

Misoprostol vaginal insert versus misoprostol vaginal tablets for the induction of labour: a cohort study
por: Bolla, Daniele, et al.
Publicado: (2018)

Protective Effects of Thymoquinone and Melatonin on Intestinal Ischemia–reperfusion Injury
por: Tas, Ufuk, et al.
Publicado: (2015)

Human Gastroenteropancreatic Expression of Melatonin and Its Receptors MT1 and MT2
por: Söderquist, Fanny, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_n66b8eigi3u6sva6pp4hs0lqc5