Changes in Nuclear Shape and Gene Expression in Response to Simulated Microgravity Are LINC Complex-Dependent

Microgravity is known to affect the organization of the cytoskeleton, cell and nuclear morphology and to elicit differential expression of genes associated with the cytoskeleton, focal adhesions and the extracellular matrix. Although the nucleus is mechanically connected to the cytoskeleton through...

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Detalles Bibliográficos
Autores principales: Neelam, Srujana, Richardson, Brian, Barker, Richard, Udave, Ceasar, Gilroy, Simon, Cameron, Mark J., Levine, Howard G., Zhang, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555797/
https://www.ncbi.nlm.nih.gov/pubmed/32942630
http://dx.doi.org/10.3390/ijms21186762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555797/
https://www.ncbi.nlm.nih.gov/pubmed/32942630
http://dx.doi.org/10.3390/ijms21186762

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