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Changes in Nuclear Shape and Gene Expression in Response to Simulated Microgravity Are LINC Complex-Dependent
Microgravity is known to affect the organization of the cytoskeleton, cell and nuclear morphology and to elicit differential expression of genes associated with the cytoskeleton, focal adhesions and the extracellular matrix. Although the nucleus is mechanically connected to the cytoskeleton through...
Autores principales: | Neelam, Srujana, Richardson, Brian, Barker, Richard, Udave, Ceasar, Gilroy, Simon, Cameron, Mark J., Levine, Howard G., Zhang, Ye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555797/ https://www.ncbi.nlm.nih.gov/pubmed/32942630 http://dx.doi.org/10.3390/ijms21186762 |
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