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The Transcriptomic Response of the Murine Thyroid Gland to Iodide Overload and the Role of the Nrf2 Antioxidant System
Background: Thyroid follicular cells have physiologically high levels of reactive oxygen species because oxidation of iodide is essential for the iodination of thyroglobulin (Tg) during thyroid hormone synthesis. Thyroid follicles (the functional units of the thyroid) also utilize incompletely under...
Autores principales: | Chartoumpekis, Dionysios V., Ziros, Panos G., Georgakopoulos-Soares, Ilias, Smith, Adam A. T., Marques, Ana Claudia, Ibberson, Mark, A. Kopp, Peter, Habeos, Ioannis, Trougakos, Ioannis P., Khoo, Nicholas K. H., Sykiotis, Gerasimos P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555824/ https://www.ncbi.nlm.nih.gov/pubmed/32961913 http://dx.doi.org/10.3390/antiox9090884 |
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