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Do Your Kids Get What You Paid for? Evaluation of Commercially Available Probiotic Products Intended for Children in the Republic of the Philippines and the Republic of Korea

A wide range of probiotic products is available on the market and can be easily purchased over the counter and unlike pharmaceutical drugs, their commercial distribution is not strictly regulated. In this study, ten probiotic preparations commercially available for children’s consumption in the Repu...

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Autores principales: Dioso, Clarizza May, Vital, Pierangeli, Arellano, Karina, Park, Haryung, Todorov, Svetoslav Dimitrov, Ji, Yosep, Holzapfel, Wilhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555838/
https://www.ncbi.nlm.nih.gov/pubmed/32899215
http://dx.doi.org/10.3390/foods9091229
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author Dioso, Clarizza May
Vital, Pierangeli
Arellano, Karina
Park, Haryung
Todorov, Svetoslav Dimitrov
Ji, Yosep
Holzapfel, Wilhelm
author_facet Dioso, Clarizza May
Vital, Pierangeli
Arellano, Karina
Park, Haryung
Todorov, Svetoslav Dimitrov
Ji, Yosep
Holzapfel, Wilhelm
author_sort Dioso, Clarizza May
collection PubMed
description A wide range of probiotic products is available on the market and can be easily purchased over the counter and unlike pharmaceutical drugs, their commercial distribution is not strictly regulated. In this study, ten probiotic preparations commercially available for children’s consumption in the Republic of the Philippines (PH) and the Republic of Korea (SK) have been investigated. The analyses included determination of viable counts and taxonomic identification of the bacterial species present in each formulation. The status of each product was assessed by comparing the results with information and claims provided on the label. In addition to their molecular identification, safety assessment of the isolated strains was conducted by testing for hemolysis, biogenic amine production and antibiotic resistance. One out of the ten products contained lower viable numbers of recovered microorganisms than claimed on the label. Enterococcus strains, although not mentioned on the label, were isolated from four products. Some of these isolates produced biogenic amines and were resistant to one or several antibiotics. Metagenomic analyses of two products revealed that one product did not contain most of the microorganisms declared in its specification. The study demonstrated that some commercial probiotic products for children did not match their label claims. Infants and young children belong to the most vulnerable members of society, and food supplements including probiotics destined for this consumer group require careful checking and strict regulation before commercial distribution.
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spelling pubmed-75558382020-10-19 Do Your Kids Get What You Paid for? Evaluation of Commercially Available Probiotic Products Intended for Children in the Republic of the Philippines and the Republic of Korea Dioso, Clarizza May Vital, Pierangeli Arellano, Karina Park, Haryung Todorov, Svetoslav Dimitrov Ji, Yosep Holzapfel, Wilhelm Foods Article A wide range of probiotic products is available on the market and can be easily purchased over the counter and unlike pharmaceutical drugs, their commercial distribution is not strictly regulated. In this study, ten probiotic preparations commercially available for children’s consumption in the Republic of the Philippines (PH) and the Republic of Korea (SK) have been investigated. The analyses included determination of viable counts and taxonomic identification of the bacterial species present in each formulation. The status of each product was assessed by comparing the results with information and claims provided on the label. In addition to their molecular identification, safety assessment of the isolated strains was conducted by testing for hemolysis, biogenic amine production and antibiotic resistance. One out of the ten products contained lower viable numbers of recovered microorganisms than claimed on the label. Enterococcus strains, although not mentioned on the label, were isolated from four products. Some of these isolates produced biogenic amines and were resistant to one or several antibiotics. Metagenomic analyses of two products revealed that one product did not contain most of the microorganisms declared in its specification. The study demonstrated that some commercial probiotic products for children did not match their label claims. Infants and young children belong to the most vulnerable members of society, and food supplements including probiotics destined for this consumer group require careful checking and strict regulation before commercial distribution. MDPI 2020-09-03 /pmc/articles/PMC7555838/ /pubmed/32899215 http://dx.doi.org/10.3390/foods9091229 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dioso, Clarizza May
Vital, Pierangeli
Arellano, Karina
Park, Haryung
Todorov, Svetoslav Dimitrov
Ji, Yosep
Holzapfel, Wilhelm
Do Your Kids Get What You Paid for? Evaluation of Commercially Available Probiotic Products Intended for Children in the Republic of the Philippines and the Republic of Korea
title Do Your Kids Get What You Paid for? Evaluation of Commercially Available Probiotic Products Intended for Children in the Republic of the Philippines and the Republic of Korea
title_full Do Your Kids Get What You Paid for? Evaluation of Commercially Available Probiotic Products Intended for Children in the Republic of the Philippines and the Republic of Korea
title_fullStr Do Your Kids Get What You Paid for? Evaluation of Commercially Available Probiotic Products Intended for Children in the Republic of the Philippines and the Republic of Korea
title_full_unstemmed Do Your Kids Get What You Paid for? Evaluation of Commercially Available Probiotic Products Intended for Children in the Republic of the Philippines and the Republic of Korea
title_short Do Your Kids Get What You Paid for? Evaluation of Commercially Available Probiotic Products Intended for Children in the Republic of the Philippines and the Republic of Korea
title_sort do your kids get what you paid for? evaluation of commercially available probiotic products intended for children in the republic of the philippines and the republic of korea
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555838/
https://www.ncbi.nlm.nih.gov/pubmed/32899215
http://dx.doi.org/10.3390/foods9091229
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