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Analysis of expression, epigenetic, and genetic changes of HNF1B in 130 kidney tumours
Hepatocyte nuclear factor 1 beta (HNF1B) is a transcription factor which plays a crucial role in nephronogenesis, and its germline mutations have been associated with kidney developmental disorders. However, the effects of HNF1B somatic exonic mutations and its role in the pathogenesis of kidney tum...
Autores principales: | Bártů, Michaela, Hojný, Jan, Hájková, Nikola, Michálková, Romana, Krkavcová, Eva, Hadravský, Ladislav, Kleissnerová, Lenka, Bui, Quang Hiep, Stružinská, Ivana, Němejcová, Kristýna, Čapoun, Otakar, Šlemendová, Monika, Dundr, Pavel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555858/ https://www.ncbi.nlm.nih.gov/pubmed/33051485 http://dx.doi.org/10.1038/s41598-020-74059-z |
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