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Single-cell RNA cap and tail sequencing (scRCAT-seq) reveals subtype-specific isoforms differing in transcript demarcation

The differences in transcription start sites (TSS) and transcription end sites (TES) among gene isoforms can affect the stability, localization, and translation efficiency of mRNA. Gene isoforms allow a single gene diverse functions across different cell types, and isoform dynamics allow different f...

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Detalles Bibliográficos
Autores principales: Hu, Youjin, Zhong, Jiawei, Xiao, Yuhua, Xing, Zheng, Sheu, Katherine, Fan, Shuxin, An, Qin, Qiu, Yuanhui, Zheng, Yingfeng, Liu, Xialin, Fan, Guoping, Liu, Yizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555861/
https://www.ncbi.nlm.nih.gov/pubmed/33051455
http://dx.doi.org/10.1038/s41467-020-18976-7