Cargando…

Inactivation of ribosomal protein S27-like impairs DNA interstrand cross-link repair by destabilization of FANCD2 and FANCI

Ribosomal protein S27-like (RPS27L), an evolutionarily conserved ribosomal protein and a direct p53 target, plays an important role in maintenance of genome integrity. We have previously reported that RPS27L regulates radiation sensitivity via the MDM2-p53 and MDM2-MRN-ATM axes. Whether and how RPS2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Siyuan, He, Hengqian, Ma, Yuanyuan, Xu, Jie, Chen, Guoan, Sun, Yi, Xiong, Xiufang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555897/ https://www.ncbi.nlm.nih.gov/pubmed/33051438 http://dx.doi.org/10.1038/s41419-020-03082-9

Ejemplares similares

The FANCD2–FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2
por: Liang, Chih-Chao, et al.
Publicado: (2016)

FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair
por: Alcón, Pablo, et al.
Publicado: (2020)

Structural insight into FANCI–FANCD2 monoubiquitination
por: Li, Landing, et al.
Publicado: (2020)

Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA
por: Longerich, Simonne, et al.
Publicado: (2014)

Binding of FANCI-FANCD2 Complex to RNA and R-Loops Stimulates Robust FANCD2 Monoubiquitination
por: Liang, Zhuobin, et al.
Publicado: (2019)

A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2
por: Dubois, Emilie L, et al.
Publicado: (2019)

DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI
por: Sato, Koichi, et al.
Publicado: (2012)

Structural and biochemical basis of interdependent FANCI‐FANCD2 ubiquitination
por: Lemonidis, Kimon, et al.
Publicado: (2022)

Coordinate Nuclear Targeting of the FANCD2 and FANCI Proteins via a FANCD2 Nuclear Localization Signal
por: Boisvert, Rebecca A., et al.
Publicado: (2013)

Phosphorylation of FANCD2 Inhibits the FANCD2/FANCI Complex and Suppresses the Fanconi Anemia Pathway in the Absence of DNA Damage
por: Lopez-Martinez, David, et al.
Publicado: (2019)

FANCI Protein Binds to DNA and Interacts with FANCD2 to Recognize Branched Structures
por: Yuan, Fenghua, et al.
Publicado: (2009)

Defective FANCI Binding by a Fanconi Anemia-Related FANCD2 Mutant
por: Sato, Koichi, et al.
Publicado: (2014)

ATR-Mediated FANCI Phosphorylation Regulates Both Ubiquitination and Deubiquitination of FANCD2
por: Tan, Winnie, et al.
Publicado: (2020)

Ribosomal protein S27-like regulates autophagy via the β-TrCP-DEPTOR-mTORC1 axis
por: Xiong, Xiufang, et al.
Publicado: (2018)

Fanconi anemia FANCD2 and FANCI proteins regulate the nuclear dynamics of splicing factors
por: Moriel-Carretero, María, et al.
Publicado: (2017)

Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA
por: Rennie, Martin L, et al.
Publicado: (2020)

FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery
por: Chaudhury, Indrajit, et al.
Publicado: (2013)

FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2
por: Castella, Maria, et al.
Publicado: (2015)

Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase
por: Sareen, Archana, et al.
Publicado: (2012)

FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response
por: Thompson, Elizabeth L., et al.
Publicado: (2017)

Monoubiquitination by the human Fanconi anemia core complex clamps FANCI:FANCD2 on DNA in filamentous arrays
por: Tan, Winnie, et al.
Publicado: (2020)

UHRF1 Is a Sensor for DNA Interstrand Crosslinks and Recruits FANCD2 to Initiate the Fanconi Anemia Pathway
por: Liang, Chih-Chao, et al.
Publicado: (2015)

FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5′-DNA end
por: Sato, Koichi, et al.
Publicado: (2016)

The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2
por: Swuec, Paolo, et al.
Publicado: (2016)

Inactivation of ribosomal protein S27-like confers radiosensitivity via the Mdm2-p53 and Mdm2–MRN–ATM axes
por: Zhao, Yongchao, et al.
Publicado: (2018)

FANCJ protein is important for the stability of FANCD2/FANCI proteins and protects them from proteasome and caspase-3 dependent degradation
por: Clark, David W., et al.
Publicado: (2015)

Repair of interstrand cross-links in DNA induced by psoralen plus light.
por: Cole, R. S.
Publicado: (1973)

DNA interstrand cross-link repair requires replication fork convergence
por: Zhang, Jieqiong, et al.
Publicado: (2015)

TRAIP is a master regulator of DNA interstrand cross-link repair
por: Wu, R. Alex, et al.
Publicado: (2019)

Preparation of DNA interstrand cross-link repair intermediates induced by abasic sites
por: Tang, Jin, et al.
Publicado: (2022)

Ribosomal protein S27-like and S27 interplay with p53-MDM2 axis s a target, a substrate, and a regulator
por: Xiong, Xiufang, et al.
Publicado: (2010)

Distinct cellular phenotype linked to defective DNA interstrand crosslink repair and homologous recombination
por: Gorniewska, Aleksandra M., et al.
Publicado: (2017)

DNA alkylation and interstrand cross-linking by treosulfan
por: Hartley, J A, et al.
Publicado: (1999)

Deubiquitination of FANCD2 Is Required for DNA Crosslink Repair
por: Oestergaard, Vibe H., et al.
Publicado: (2007)

Fancy & imagination
por: Brett, R. L.
Publicado: (1969)

Fancy Fees
Publicado: (1888)

Facts and Fancies
Publicado: (1897)

Facts and Fancies
Publicado: (1897)

FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation
por: Wang, Jingming, et al.
Publicado: (2016)

Mechanisms of interstrand DNA crosslink repair and human disorders
por: Hashimoto, Satoru, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_eqrik2c0oot92rp52nbc7ik6m7