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NLRP3-dependent microglial training impaired the clearance of amyloid-beta and aggravated the cognitive decline in Alzheimer’s disease

Alzheimer’s disease (AD), the most common form of dementia, is marked by progressive cognitive decline, deposition of misfolded amyloid-β (Aβ) peptide and formation of neurofibrillary tangles. Recently, microglial training has emerged as an important contributor to neurological diseases, which augme...

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Detalles Bibliográficos
Autores principales:	He, Xiao-fei, Xu, Jing-hui, Li, Ge, Li, Ming-yue, Li, Li-li, Pei, Zhong, Zhang, Li-ying, Hu, Xi-quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555905/ https://www.ncbi.nlm.nih.gov/pubmed/33051464 http://dx.doi.org/10.1038/s41419-020-03072-x

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