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Seroprevalence of Antibodies against SARS-CoV-2 among the Personnel and Students of the National and Kapodistrian University of Athens, Greece: A Preliminary Report

Due to early implementation of public health measures, Greece had low number of SARS-CoV-2 infections and COVID-19 severe incidents in hospitalized patients. The National and Kapodistrian University of Athens (ΝΚUA), especially its health-care/medical personnel, has been actively involved in the fir...

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Autores principales: Tsitsilonis, Ourania E., Paraskevis, Dimitrios, Lianidou, Evi, Pierros, Vassilios, Akalestos, Athanasios, Kastritis, Efstathios, Moutsatsou, Paraskevi, Scorilas, Andreas, Sphicopoulos, Thomas, Terpos, Evangelos, Thomaidis, Nikolaos, Tsakris, Athanassios, Voulgaris, Nikolaos, Daskalaki, Christina C., Evangelakou, Zoi, Fouki, Christina, Gianniou, Despoina D., Gumeni, Sentiljana, Kostaki, Evangelia-Georgia, Kostopoulos, Ioannis V., Manola, Maria S., Orologas-Stavrou, Nikolaos, Panteli, Chrysanthi, Papanagnou, Eleni-Dimitra, Rousakis, Pantelis, Sklirou, Aimilia D., Smilkou, Stavroula, Stergiopoulou, Dimitra, Trougakos, Ioannis P., Tsiodras, Soritios, Sfikakis, Petros P., Dimopoulos, Meletios-Athanasios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555935/
https://www.ncbi.nlm.nih.gov/pubmed/32967110
http://dx.doi.org/10.3390/life10090214
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author Tsitsilonis, Ourania E.
Paraskevis, Dimitrios
Lianidou, Evi
Pierros, Vassilios
Akalestos, Athanasios
Kastritis, Efstathios
Moutsatsou, Paraskevi
Scorilas, Andreas
Sphicopoulos, Thomas
Terpos, Evangelos
Thomaidis, Nikolaos
Tsakris, Athanassios
Voulgaris, Nikolaos
Daskalaki, Christina C.
Evangelakou, Zoi
Fouki, Christina
Gianniou, Despoina D.
Gumeni, Sentiljana
Kostaki, Evangelia-Georgia
Kostopoulos, Ioannis V.
Manola, Maria S.
Orologas-Stavrou, Nikolaos
Panteli, Chrysanthi
Papanagnou, Eleni-Dimitra
Rousakis, Pantelis
Sklirou, Aimilia D.
Smilkou, Stavroula
Stergiopoulou, Dimitra
Trougakos, Ioannis P.
Tsiodras, Soritios
Sfikakis, Petros P.
Dimopoulos, Meletios-Athanasios
author_facet Tsitsilonis, Ourania E.
Paraskevis, Dimitrios
Lianidou, Evi
Pierros, Vassilios
Akalestos, Athanasios
Kastritis, Efstathios
Moutsatsou, Paraskevi
Scorilas, Andreas
Sphicopoulos, Thomas
Terpos, Evangelos
Thomaidis, Nikolaos
Tsakris, Athanassios
Voulgaris, Nikolaos
Daskalaki, Christina C.
Evangelakou, Zoi
Fouki, Christina
Gianniou, Despoina D.
Gumeni, Sentiljana
Kostaki, Evangelia-Georgia
Kostopoulos, Ioannis V.
Manola, Maria S.
Orologas-Stavrou, Nikolaos
Panteli, Chrysanthi
Papanagnou, Eleni-Dimitra
Rousakis, Pantelis
Sklirou, Aimilia D.
Smilkou, Stavroula
Stergiopoulou, Dimitra
Trougakos, Ioannis P.
Tsiodras, Soritios
Sfikakis, Petros P.
Dimopoulos, Meletios-Athanasios
author_sort Tsitsilonis, Ourania E.
collection PubMed
description Due to early implementation of public health measures, Greece had low number of SARS-CoV-2 infections and COVID-19 severe incidents in hospitalized patients. The National and Kapodistrian University of Athens (ΝΚUA), especially its health-care/medical personnel, has been actively involved in the first line of state responses to COVID-19. To estimate the prevalence of antibodies (Igs) against SARS-CoV-2 among NKUA members, we designed a five consecutive monthly serosurvey among randomly selected NKUA consenting volunteers. Here, we present the results from the first 2500 plasma samples collected during June–July 2020. Twenty-five donors were tested positive for anti-SARS-CoV-2 Igs; thus, the overall seroprevalence was 1.00%. The weighted overall seroprevalence was 0.93% (95% CI: 0.27, 2.09) and varied between males [1.05% (95% CI: 0.18, 2.92)] and females [0.84% (95% CI: 0.13, 2.49)], age-groups and different categories (higher in participants from the School of Health Sciences and in scientific affiliates/faculty members/laboratory assistants), but no statistical differences were detected. Although focused on the specific population of NKUA members, our study shows that the prevalence of anti-SARS-CoV-2 Igs for the period June–July 2020 remained low and provides knowledge of public health importance for the NKUA members. Given that approximately one in three infections was asymptomatic, continuous monitoring of the progression of the pandemic by assessing Ig seroprevalence is needed.
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spelling pubmed-75559352020-10-19 Seroprevalence of Antibodies against SARS-CoV-2 among the Personnel and Students of the National and Kapodistrian University of Athens, Greece: A Preliminary Report Tsitsilonis, Ourania E. Paraskevis, Dimitrios Lianidou, Evi Pierros, Vassilios Akalestos, Athanasios Kastritis, Efstathios Moutsatsou, Paraskevi Scorilas, Andreas Sphicopoulos, Thomas Terpos, Evangelos Thomaidis, Nikolaos Tsakris, Athanassios Voulgaris, Nikolaos Daskalaki, Christina C. Evangelakou, Zoi Fouki, Christina Gianniou, Despoina D. Gumeni, Sentiljana Kostaki, Evangelia-Georgia Kostopoulos, Ioannis V. Manola, Maria S. Orologas-Stavrou, Nikolaos Panteli, Chrysanthi Papanagnou, Eleni-Dimitra Rousakis, Pantelis Sklirou, Aimilia D. Smilkou, Stavroula Stergiopoulou, Dimitra Trougakos, Ioannis P. Tsiodras, Soritios Sfikakis, Petros P. Dimopoulos, Meletios-Athanasios Life (Basel) Communication Due to early implementation of public health measures, Greece had low number of SARS-CoV-2 infections and COVID-19 severe incidents in hospitalized patients. The National and Kapodistrian University of Athens (ΝΚUA), especially its health-care/medical personnel, has been actively involved in the first line of state responses to COVID-19. To estimate the prevalence of antibodies (Igs) against SARS-CoV-2 among NKUA members, we designed a five consecutive monthly serosurvey among randomly selected NKUA consenting volunteers. Here, we present the results from the first 2500 plasma samples collected during June–July 2020. Twenty-five donors were tested positive for anti-SARS-CoV-2 Igs; thus, the overall seroprevalence was 1.00%. The weighted overall seroprevalence was 0.93% (95% CI: 0.27, 2.09) and varied between males [1.05% (95% CI: 0.18, 2.92)] and females [0.84% (95% CI: 0.13, 2.49)], age-groups and different categories (higher in participants from the School of Health Sciences and in scientific affiliates/faculty members/laboratory assistants), but no statistical differences were detected. Although focused on the specific population of NKUA members, our study shows that the prevalence of anti-SARS-CoV-2 Igs for the period June–July 2020 remained low and provides knowledge of public health importance for the NKUA members. Given that approximately one in three infections was asymptomatic, continuous monitoring of the progression of the pandemic by assessing Ig seroprevalence is needed. MDPI 2020-09-21 /pmc/articles/PMC7555935/ /pubmed/32967110 http://dx.doi.org/10.3390/life10090214 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Tsitsilonis, Ourania E.
Paraskevis, Dimitrios
Lianidou, Evi
Pierros, Vassilios
Akalestos, Athanasios
Kastritis, Efstathios
Moutsatsou, Paraskevi
Scorilas, Andreas
Sphicopoulos, Thomas
Terpos, Evangelos
Thomaidis, Nikolaos
Tsakris, Athanassios
Voulgaris, Nikolaos
Daskalaki, Christina C.
Evangelakou, Zoi
Fouki, Christina
Gianniou, Despoina D.
Gumeni, Sentiljana
Kostaki, Evangelia-Georgia
Kostopoulos, Ioannis V.
Manola, Maria S.
Orologas-Stavrou, Nikolaos
Panteli, Chrysanthi
Papanagnou, Eleni-Dimitra
Rousakis, Pantelis
Sklirou, Aimilia D.
Smilkou, Stavroula
Stergiopoulou, Dimitra
Trougakos, Ioannis P.
Tsiodras, Soritios
Sfikakis, Petros P.
Dimopoulos, Meletios-Athanasios
Seroprevalence of Antibodies against SARS-CoV-2 among the Personnel and Students of the National and Kapodistrian University of Athens, Greece: A Preliminary Report
title Seroprevalence of Antibodies against SARS-CoV-2 among the Personnel and Students of the National and Kapodistrian University of Athens, Greece: A Preliminary Report
title_full Seroprevalence of Antibodies against SARS-CoV-2 among the Personnel and Students of the National and Kapodistrian University of Athens, Greece: A Preliminary Report
title_fullStr Seroprevalence of Antibodies against SARS-CoV-2 among the Personnel and Students of the National and Kapodistrian University of Athens, Greece: A Preliminary Report
title_full_unstemmed Seroprevalence of Antibodies against SARS-CoV-2 among the Personnel and Students of the National and Kapodistrian University of Athens, Greece: A Preliminary Report
title_short Seroprevalence of Antibodies against SARS-CoV-2 among the Personnel and Students of the National and Kapodistrian University of Athens, Greece: A Preliminary Report
title_sort seroprevalence of antibodies against sars-cov-2 among the personnel and students of the national and kapodistrian university of athens, greece: a preliminary report
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555935/
https://www.ncbi.nlm.nih.gov/pubmed/32967110
http://dx.doi.org/10.3390/life10090214
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