Lack of PPARβ/δ-Inactivated SGK-1 Is Implicated in Liver Carcinogenesis

OBJECTIVE: The present study examined the role of PPARβ/δ in hepatocellular carcinoma (HCC). METHODS: The effect of PPARβ/δ on HCC development was analyzed using PPARβ/δ-overexpressed liver cancer cells and PPARβ/δ-knockout mouse models. RESULTS: PPARβ/δ((-/-)) mice were susceptible to diethylnitros...

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Detalles Bibliográficos
Autores principales: Shen, Bo, Li, Aimin, Wan, Yu-Jui Yvonne, Shen, Guijia, Zhu, Jinshui, Nie, Yuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556072/
https://www.ncbi.nlm.nih.gov/pubmed/33083492
http://dx.doi.org/10.1155/2020/9563851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556072/
https://www.ncbi.nlm.nih.gov/pubmed/33083492
http://dx.doi.org/10.1155/2020/9563851

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