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Lack of PPARβ/δ-Inactivated SGK-1 Is Implicated in Liver Carcinogenesis

OBJECTIVE: The present study examined the role of PPARβ/δ in hepatocellular carcinoma (HCC). METHODS: The effect of PPARβ/δ on HCC development was analyzed using PPARβ/δ-overexpressed liver cancer cells and PPARβ/δ-knockout mouse models. RESULTS: PPARβ/δ((-/-)) mice were susceptible to diethylnitros...

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Detalles Bibliográficos
Autores principales:	Shen, Bo, Li, Aimin, Wan, Yu-Jui Yvonne, Shen, Guijia, Zhu, Jinshui, Nie, Yuqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556072/ https://www.ncbi.nlm.nih.gov/pubmed/33083492 http://dx.doi.org/10.1155/2020/9563851

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