Cargando…

1′H-Indole-3′-Carbonyl-Thiazole-4-Carboxylic Acid Methyl Ester Blocked Human Glioma Cell Invasion via Aryl Hydrocarbon Receptor's Regulation of Cytoskeletal Contraction

Blocking glioma cell invasion has been challenging due to cancer cells that can swiftly switch their migration mode, and agents that can block more than one migration mode are sought after. We found that small molecule 2-(1H-indole-3-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE), an endoge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Lijiao, Shu, Qiuting, Sun, Hui, Ma, Yunlong, Kang, Dandan, Zhao, Yating, Lu, Jing, Gong, Pei, Yang, Fan, Wan, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556083/ https://www.ncbi.nlm.nih.gov/pubmed/33083460 http://dx.doi.org/10.1155/2020/2616930

Ejemplares similares

Ruthenium‐Catalyzed C−H Arylation of Benzoic Acids and Indole Carboxylic Acids with Aryl Halides
por: Simonetti, Marco, et al.
Publicado: (2016)

Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles
por: Hubbard, Troy D., et al.
Publicado: (2015)

Characterization of marine-derived halogenated indoles as ligands of the aryl hydrocarbon receptor
por: King, Jessie, et al.
Publicado: (2022)

Methyl 2-(tert-butoxycarbonylamino)-1,3-thiazole-5-carboxylate
por: An, Kang, et al.
Publicado: (2010)

Indole-3-pyruvic acid alleviates rheumatoid arthritis via the aryl hydrocarbon receptor pathway
por: Huang, Tai, et al.
Publicado: (2023)

A concise flow synthesis of indole-3-carboxylic ester and its derivatisation to an auxin mimic
por: Baumann, Marcus, et al.
Publicado: (2017)

Chiral Brønsted Acid‐Catalyzed Asymmetric Synthesis of N‐Aryl‐cis‐aziridine Carboxylate Esters
por: Bew, Sean P., et al.
Publicado: (2017)

Gut Microbiota-Derived Indole-3-Carboxylate Influences Mucosal Integrity and Immunity Through the Activation of the Aryl Hydrocarbon Receptors and Nutrient Transporters in Broiler Chickens Challenged With Eimeria maxima
por: Park, Inkyung, et al.
Publicado: (2022)

Rhodium-catalyzed reductive carbonylation of aryl iodides to arylaldehydes with syngas
por: Liu, Zhenghui, et al.
Publicado: (2020)

Indole Treatment Alleviates Intestinal Tissue Damage Induced by Chicken Coccidiosis Through Activation of the Aryl Hydrocarbon Receptor
por: Kim, Woo H., et al.
Publicado: (2019)

Indole-3-Carbinol-Dependent Aryl Hydrocarbon Receptor Signaling Attenuates the Inflammatory Response in Experimental Necrotizing Enterocolitis
por: Nolan, Lila S., et al.
Publicado: (2021)

Palladium-catalyzed benzylic C(sp(3))–H carbonylative arylation of azaarylmethyl amines with aryl bromides
por: Zhao, Haoqiang, et al.
Publicado: (2021)

Synthesis, antioxidant and antimicrobial properties of novel pyridyl-carbonyl thiazoles as dendrodoine analogs
por: ŞAHİN, Zafer, et al.
Publicado: (2020)

Autocatalytic Carbonyl Arylation through In Situ Release of Aryl Nucleophiles from N‐Aryl‐N′‐Silyldiazenes
por: Chauvier, Clément, et al.
Publicado: (2020)

Role of the Aryl Hydrocarbon Receptor and Gut Microbiota-Derived Metabolites Indole-3-Acetic Acid in Sulforaphane Alleviates Hepatic Steatosis in Mice
por: Xu, Xiuxiu, et al.
Publicado: (2021)

A new route to synthesize aryl acetates from carbonylation of aryl methyl ethers
por: Mei, Qingqing, et al.
Publicado: (2018)

Involvement of Aryl Hydrocarbon Receptor and Aryl Hydrocarbon Receptor Repressor in Helicobacter Pylori-related Gastric Pathogenesis
por: Zhu, Renfei, et al.
Publicado: (2018)

Metabolites of Latilactobacillus curvatus BYB3 and Indole Activate Aryl Hydrocarbon Receptor to Attenuate Lipopolysaccharide-Induced Intestinal Barrier Dysfunction
por: Wang, Xing, et al.
Publicado: (2022)

The Impact of Indoles Activating the Aryl Hydrocarbon Receptor on Androgen Receptor Activity in the 22Rv1 Prostate Cancer Cell Line
por: Zgarbová, Eliška, et al.
Publicado: (2022)

Lactobacillus-derived indole-3-lactic acid ameliorates colitis in cesarean-born offspring via activation of aryl hydrocarbon receptor
por: Xia, Yanan, et al.
Publicado: (2023)

The aryl hydrocarbon receptor in tumor immunity
por: Platten, Michael, et al.
Publicado: (2012)

Antioxidant Functions of the Aryl Hydrocarbon Receptor
por: Dietrich, Cornelia
Publicado: (2016)

Aryl Hydrocarbon Receptor and Stem Cells
por: Gasiewicz, Thomas A., et al.
Publicado: (2017)

The Aryl Hydrocarbon Receptor and Tumor Immunity
por: Xue, Ping, et al.
Publicado: (2018)

The Aryl Hydrocarbon Receptor and the Nervous System
por: Juricek, Ludmila, et al.
Publicado: (2018)

The aryl hydrocarbon receptor in liver inflammation
por: Carambia, Antonella, et al.
Publicado: (2021)

Synthesis of New Functionalized Indoles Based on Ethyl Indol-2-carboxylate
por: Boraei, Ahmed T. A., et al.
Publicado: (2016)

Recent Progress Concerning the N-Arylation of Indoles
por: Oeser, Petr, et al.
Publicado: (2021)

C4-arylation and domino C4-arylation/3,2-carbonyl migration of indoles by tuning Pd catalytic modes: Pd(i)–Pd(ii) catalysis vs. Pd(ii) catalysis
por: Cheng, Yaohang, et al.
Publicado: (2021)

Ginsenosides Are Novel Naturally-Occurring Aryl Hydrocarbon Receptor Ligands
por: Hu, Qin, et al.
Publicado: (2013)

Rhodium-catalyzed, P-directed selective C7 arylation of indoles
por: Qiu, Xiaodong, et al.
Publicado: (2018)

Rapid assessment of conformational preferences in biaryl and aryl carbonyl fragments
por: Gutiérrez Sanfeliciano, Sonia Maria, et al.
Publicado: (2018)

Chemospecific Cyclizations of α‐Carbonyl Sulfoxonium Ylides on Aryls and Heteroaryls
por: Clare, Daniel, et al.
Publicado: (2019)

Modular synthesis of α-arylated carboxylic acids, esters and amides via photocatalyzed triple C–F bond cleavage of methyltrifluorides
por: Li, Sifan, et al.
Publicado: (2022)

4-Dimethylaminopyridine-Catalyzed Metal-Free Aerobic Oxidation of Aryl α-Halo Esters to Aryl α-Keto Esters
por: Jung, Yeonghun, et al.
Publicado: (2020)

Ruthenium-Catalyzed C–H Arylation of Diverse Aryl Carboxylic Acids with Aryl and Heteroaryl Halides
por: Huang, Liangbin, et al.
Publicado: (2016)

Carboxylic ester hydrolases from hyperthermophiles
por: Levisson, Mark, et al.
Publicado: (2009)

Synthesis of Carbonyl-Containing Oxindoles via Ni-Catalyzed Reductive Aryl-Acylation and Aryl-Esterification of Alkenes
por: Ding, Zhengtian, et al.
Publicado: (2022)

Development of a Method for the N-Arylation of Amino Acid Esters with Aryl Triflates
por: King, Sandra M., et al.
Publicado: (2016)

Binding of polychlorinated biphenyls to the aryl hydrocarbon receptor.
por: Kafafi, S A, et al.
Publicado: (1993)

Cannot write session to /tmp/vufind_sessions/sess_he61nmpa020gedu8fco1d1s3to