Cargando…

Asparagine and Glutamine Side-Chains and Ladders in HET-s(218–289) Amyloid Fibrils Studied by Fast Magic-Angle Spinning NMR

Asparagine and glutamine side-chains can form hydrogen-bonded ladders which contribute significantly to the stability of amyloid fibrils. We show, using the example of HET-s(218–289) fibrils, that the primary amide side-chain proton resonances can be detected in cross-polarization based solid-state...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wiegand, Thomas, Malär, Alexander A., Cadalbert, Riccardo, Ernst, Matthias, Böckmann, Anja, Meier, Beat H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556116/ https://www.ncbi.nlm.nih.gov/pubmed/33195425 http://dx.doi.org/10.3389/fmolb.2020.582033

Ejemplares similares

Localized and Collective Motions in HET‐s(218‐289) Fibrils from Combined NMR Relaxation and MD Simulation
por: Smith, Albert A., et al.
Publicado: (2019)

Protein Side-Chain–DNA Contacts Probed by Fast Magic-Angle Spinning NMR
por: Lacabanne, Denis, et al.
Publicado: (2020)

Residual dipolar line width in magic-angle spinning proton solid-state NMR
por: Chávez, Matías, et al.
Publicado: (2021)

Sedimentation Yields Long-Term Stable Protein Samples as Shown by Solid-State NMR
por: Wiegand, Thomas, et al.
Publicado: (2020)

Protein NMR Spectroscopy at 150 kHz Magic‐Angle Spinning Continues To Improve Resolution and Mass Sensitivity
por: Schledorn, Maarten, et al.
Publicado: (2020)

Temperature-Dependent Solid-State NMR Proton Chemical-Shift Values and Hydrogen Bonding
por: Malär, Alexander A., et al.
Publicado: (2021)

Nucleotide Binding Modes in a Motor Protein Revealed by (31)P‐ and (1)H‐Detected MAS Solid‐State NMR Spectroscopy
por: Wiegand, Thomas, et al.
Publicado: (2019)

Fast Magic‐Angle‐Spinning NMR Reveals the Evasive Hepatitis B Virus Capsid C‐Terminal Domain
por: Callon, Morgane, et al.
Publicado: (2022)

Correction of field instabilities in biomolecular solid-state NMR by simultaneous acquisition of a frequency reference
por: Římal, Václav, et al.
Publicado: (2022)

Determination of Histidine Protonation States in Proteins by Fast Magic Angle Spinning NMR
por: Zadorozhnyi, Roman, et al.
Publicado: (2021)

Fiber Diffraction of the Prion-Forming Domain HET-s(218–289) Shows Dehydration-Induced Deformation of a Complex Amyloid Structure
por: Wan, William, et al.
Publicado: (2014)

100 kHz MAS Proton-Detected NMR Spectroscopy of Hepatitis B Virus Capsids
por: Lecoq, Lauriane, et al.
Publicado: (2019)

Experimental Characterization of the Hepatitis B Virus Capsid Dynamics by Solid-State NMR
por: Malär, Alexander A., et al.
Publicado: (2022)

Including Protons in Solid-State NMR Resonance Assignment and Secondary Structure Analysis: The Example of RNA Polymerase II Subunits Rpo4/7
por: Torosyan, Anahit, et al.
Publicado: (2019)

Paramagnetic Solid‐State NMR to Localize the Metal‐Ion Cofactor in an Oligomeric DnaB Helicase
por: Zehnder, Johannes, et al.
Publicado: (2021)

Efficient and stable reconstitution of the ABC transporter BmrA for solid-state NMR studies
por: Kunert, Britta, et al.
Publicado: (2014)

Combining Cell-Free Protein Synthesis and NMR Into a Tool to Study Capsid Assembly Modulation
por: Wang, Shishan, et al.
Publicado: (2019)

High and fast: NMR protein–proton side-chain assignments at 160 kHz and 1.2 GHz
por: Callon, Morgane, et al.
Publicado: (2023)

The Mechanism of Toxicity in HET-S/HET-s Prion Incompatibility
por: Seuring, Carolin, et al.
Publicado: (2012)

Alternative salt bridge formation in Aβ—a hallmark of early-onset Alzheimer's disease?
por: Schledorn, Maarten, et al.
Publicado: (2015)

The conformational changes coupling ATP hydrolysis and translocation in a bacterial DnaB helicase
por: Wiegand, Thomas, et al.
Publicado: (2019)

Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma
por: Ratnikov, Boris, et al.
Publicado: (2015)

Controlling the prion propensity of glutamine/asparagine-rich proteins
por: Paul, Kacy R, et al.
Publicado: (2015)

Spinning faster: protein NMR at MAS frequencies up to 126 kHz
por: Penzel, Susanne, et al.
Publicado: (2019)

Biomolecular solid-state NMR spectroscopy at 1200 MHz: the gain in resolution
por: Callon, Morgane, et al.
Publicado: (2021)

High-Resolution Magic-Angle-Spinning NMR in Revealing Hepatoblastoma Hallmarks
por: Tasic, Ljubica, et al.
Publicado: (2022)

Asparagine, a critical limiting metabolite during glutamine starvation
por: Jiang, Jie, et al.
Publicado: (2018)

Asparagine, colorectal cancer, and the role of sex, genes, microbes, and diet: A narrative review
por: Shen, Xinyi, et al.
Publicado: (2022)

Microfabricated Inserts for Magic Angle Coil Spinning (MACS) Wireless NMR Spectroscopy
por: Badilita, Vlad, et al.
Publicado: (2012)

Rapid Proton-Detected NMR Assignment for Proteins with Fast Magic Angle Spinning
por: Barbet-Massin, Emeline, et al.
Publicado: (2014)

Proton-detected fast-magic-angle spinning NMR of paramagnetic inorganic solids
por: Blahut, Jan, et al.
Publicado: (2021)

In-Cell Quantification of Drugs by Magic-Angle Spinning Dynamic Nuclear Polarization NMR
por: Bertarello, Andrea, et al.
Publicado: (2022)

(1)H-Detected Biomolecular NMR under Fast Magic-Angle Spinning
por: Le Marchand, Tanguy, et al.
Publicado: (2022)

Deamidation Reactions of Asparagine- and Glutamine-Containing Dipeptides Investigated by Ion Spectroscopy
por: Kempkes, Lisanne J. M., et al.
Publicado: (2016)

Primary cilia sense glutamine availability and respond via asparagine synthetase
por: Steidl, Maria Elena, et al.
Publicado: (2023)

High-spin states of $^{218}$Th
por: O'Donnell, D, et al.
Publicado: (2020)

Protein fold determined by paramagnetic magic-angle spinning solid-state NMR spectroscopy
por: Sengupta, Ishita, et al.
Publicado: (2012)

Metabolite localization in living drosophila using High Resolution Magic Angle Spinning NMR
por: Sarou-Kanian, Vincent, et al.
Publicado: (2015)

Proton-Detected Solid-State NMR Spectroscopy of Bone with Ultrafast Magic Angle Spinning
por: Mroue, Kamal H., et al.
Publicado: (2015)

Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR
por: Lu, Manman, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_v7sc00k1ibl0ui934bfkj42b8b