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Successful transfer of anti–SARS-CoV-2 immunity using convalescent plasma in an MM patient with hypogammaglobulinemia and COVID-19

A severely immunocompromised patient with MM and COVID19 who received a convalescent plasma product showed SARS-CoV-2 clearance. The convalescent plasma showed humoral immunity against all structural SARS-CoV-2 proteins, which was successfully transferred to the patient.

Detalles Bibliográficos
Autores principales: Luetkens, Tim, Metcalf, Ryan, Planelles, Vicente, Zheng, Yue, Larragoite, Erin T., Spivak, Emily S., Spivak, Adam M., Steinbach, Mary, Blaylock, Robert C., Avila, Stephanie V., Hankey, Kim G., Martins, Thomas B., Slev, Patricia R., Mannuel, Heather D., Sajadi, Mohammad, Rapoport, Aaron P., Atanackovic, Djordje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556131/
https://www.ncbi.nlm.nih.gov/pubmed/33031540
http://dx.doi.org/10.1182/bloodadvances.2020002595
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author Luetkens, Tim
Metcalf, Ryan
Planelles, Vicente
Zheng, Yue
Larragoite, Erin T.
Spivak, Emily S.
Spivak, Adam M.
Steinbach, Mary
Blaylock, Robert C.
Avila, Stephanie V.
Hankey, Kim G.
Martins, Thomas B.
Slev, Patricia R.
Mannuel, Heather D.
Sajadi, Mohammad
Rapoport, Aaron P.
Atanackovic, Djordje
author_facet Luetkens, Tim
Metcalf, Ryan
Planelles, Vicente
Zheng, Yue
Larragoite, Erin T.
Spivak, Emily S.
Spivak, Adam M.
Steinbach, Mary
Blaylock, Robert C.
Avila, Stephanie V.
Hankey, Kim G.
Martins, Thomas B.
Slev, Patricia R.
Mannuel, Heather D.
Sajadi, Mohammad
Rapoport, Aaron P.
Atanackovic, Djordje
author_sort Luetkens, Tim
collection PubMed
description A severely immunocompromised patient with MM and COVID19 who received a convalescent plasma product showed SARS-CoV-2 clearance. The convalescent plasma showed humoral immunity against all structural SARS-CoV-2 proteins, which was successfully transferred to the patient.
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spelling pubmed-75561312020-10-14 Successful transfer of anti–SARS-CoV-2 immunity using convalescent plasma in an MM patient with hypogammaglobulinemia and COVID-19 Luetkens, Tim Metcalf, Ryan Planelles, Vicente Zheng, Yue Larragoite, Erin T. Spivak, Emily S. Spivak, Adam M. Steinbach, Mary Blaylock, Robert C. Avila, Stephanie V. Hankey, Kim G. Martins, Thomas B. Slev, Patricia R. Mannuel, Heather D. Sajadi, Mohammad Rapoport, Aaron P. Atanackovic, Djordje Blood Adv Exceptional Case Report A severely immunocompromised patient with MM and COVID19 who received a convalescent plasma product showed SARS-CoV-2 clearance. The convalescent plasma showed humoral immunity against all structural SARS-CoV-2 proteins, which was successfully transferred to the patient. American Society of Hematology 2020-10-08 /pmc/articles/PMC7556131/ /pubmed/33031540 http://dx.doi.org/10.1182/bloodadvances.2020002595 Text en This article is made available via the PMC Open Access Subset for unrestricted reuse and analyses in any form or by any means with acknowledgment of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.
spellingShingle Exceptional Case Report
Luetkens, Tim
Metcalf, Ryan
Planelles, Vicente
Zheng, Yue
Larragoite, Erin T.
Spivak, Emily S.
Spivak, Adam M.
Steinbach, Mary
Blaylock, Robert C.
Avila, Stephanie V.
Hankey, Kim G.
Martins, Thomas B.
Slev, Patricia R.
Mannuel, Heather D.
Sajadi, Mohammad
Rapoport, Aaron P.
Atanackovic, Djordje
Successful transfer of anti–SARS-CoV-2 immunity using convalescent plasma in an MM patient with hypogammaglobulinemia and COVID-19
title Successful transfer of anti–SARS-CoV-2 immunity using convalescent plasma in an MM patient with hypogammaglobulinemia and COVID-19
title_full Successful transfer of anti–SARS-CoV-2 immunity using convalescent plasma in an MM patient with hypogammaglobulinemia and COVID-19
title_fullStr Successful transfer of anti–SARS-CoV-2 immunity using convalescent plasma in an MM patient with hypogammaglobulinemia and COVID-19
title_full_unstemmed Successful transfer of anti–SARS-CoV-2 immunity using convalescent plasma in an MM patient with hypogammaglobulinemia and COVID-19
title_short Successful transfer of anti–SARS-CoV-2 immunity using convalescent plasma in an MM patient with hypogammaglobulinemia and COVID-19
title_sort successful transfer of anti–sars-cov-2 immunity using convalescent plasma in an mm patient with hypogammaglobulinemia and covid-19
topic Exceptional Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556131/
https://www.ncbi.nlm.nih.gov/pubmed/33031540
http://dx.doi.org/10.1182/bloodadvances.2020002595
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