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Curcumin improves necrotising microscopic colitis and cell pyroptosis by activating SIRT1/NRF2 and inhibiting the TLR4 signalling pathway in newborn rats

This study aimed to explore comprehensively the biological function of curcumin, and its underlying mechanism, in protecting from necrotising microscopic colitis in newborn rats. A total of 20 normal healthy rats were selected, and a necrotising enterocolitis (NEC) model was established. After hypox...

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Detalles Bibliográficos
Autores principales: Yin, Yiyu, Wu, Xiaole, Peng, Bei, Zou, Huaxin, Li, Shixian, Wang, Jian, Cao, Junhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556186/
https://www.ncbi.nlm.nih.gov/pubmed/32924710
http://dx.doi.org/10.1177/1753425920933656